Holistic Health Pillars

What is Holistic Health? Holistic health practitioners work with clients to achieve specific health goals. This may include improving athletic performance, disease prevention, and the treatment of symptoms. Holistic nutritionists may help implement anti-inflammatory diets. Holistic health practitioners work with both medical professionals and the public to implement a personalized plan of action. Holistic health…

What is Holistic Health? Holistic health practitioners work with clients to achieve specific health goals. This may include improving athletic performance, disease prevention, and the treatment of symptoms. Holistic nutritionists may help implement anti-inflammatory diets. Holistic health practitioners work with both medical professionals and the public to implement a personalized plan of action. Holistic health practitioners are available in many locations, and many practices are affiliated with local hospitals and clinics.

Eight pillars that support holistic health

A balanced diet is a key component of the physical wellness pillar. In addition to eating more fruits and vegetables, you should also be eating a variety of whole grains. Avoid foods with high amounts of sodium, cholesterol, or added sugar. Likewise, you should avoid fried foods. These foods can contribute to high cholesterol levels, which can have negative effects on your overall health. A healthy diet can improve many of the other pillars.

The physical and emotional aspects of health go hand in hand. Holistic health acknowledges the role of mental, spiritual, and social aspects of health. As a result, it takes the whole person into account, focusing on the connections between the body, mind, and environment. Emotional wellness is an important component of holistic health, and it can be cultivated through the eight pillars of holistic health. Listed below are the eight pillars of holistic health.

Physical health: Exercise, diet, sleep habits, hygiene, and personal hygiene are important aspects of physical health. Physical health requires adequate exercise, good rest, and a clean environment. Physical health is just the tip of the iceberg, though. It also requires that you understand your body’s chemistry and how to balance it. Nutrition is an essential part of physical health, and it gets its own pillar. Taking care of your body’s chemistry is important when making dietary and lifestyle decisions.

Cost control

There are two methods of cost control in holistic health care. One is to measure the cost of an entire system and implement changes in management based on results. Cost control in holistic health care is often difficult to achieve because costs vary according to the type of treatment provided. The other method is to identify the cost of an individual patient, and to measure the proportion of that patient who will need further care. Although holistic health care is more expensive than usual medical care, it is cost effective and can reduce mortality.

The first strategy is a health share plan, which requires the members to pay a portion of the cost of their care. These plans are more expensive than traditional medical care, but are often more effective because they treat the whole person and encourage preventative care. This approach also keeps costs low and satisfaction high, leaving more money for major medical events. The most common holistic health care costs are due to chronic illnesses and other conditions. The costs of a health share plan are shared by all members.

Another strategy for cost control in holistic health care is to use health policy commissions. The Maryland commission, for example, has been focusing on the total cost of care and hospital budgets. It has a history, and stakeholders have a vested interest in working with it. In Maryland, a Medicare waiver encourages health care providers to offer services to all payers, such as Medicare and Medicaid. These charges are then offset by increases in commercial rates.

Prevention of disease

The American Holistic Health Association advocates for the prevention of chronic disease. The emphasis on holistic health entails treating the entire person, incorporating the mind, body, and spirit into a health-promoting lifestyle. The most difficult aspects of incorporating holistic practices into the client’s life are often changes to food, which can be hard for clients to accept. However, the benefits of holistic health far outweigh the negative effects.

One of the most significant benefits of preventive medicine is lower healthcare costs. The Centers for Disease Control and Prevention report that the practice of prevention can reduce costs by more than $1 trillion annually. In fact, 90 percent of healthcare expenditures are related to chronic conditions. Preventive care focuses on the prevention of chronic disease by emphasizing long-term health, healthy pregnancy, and aging. Health screenings are an important component of this holistic approach.

The benefits of holistic medicine are numerous. First, holistic doctors focus on the whole person, rather than simply treating the symptoms of an illness. Holistic physicians believe that the mind-body connection is the key to healing. As such, holistic doctors help patients develop an understanding of their entire health profile. By integrating complementary therapies and Western medicine, holistic physicians can treat the whole person and prevent or improve disease symptoms. In addition to reducing disease risk, holistic health also emphasizes a strong doctor-patient relationship.

Medicinal plants

Medicinal plants can be used to treat various illnesses and diseases. Using them can be a natural way to improve your overall health and well-being. Here are some tips for maximizing their benefits. Read on to learn how to use medicinal plants in your daily life. We are going to go over a few examples of the most popular ones and how they can improve your health. Listed below are some of their most important benefits.

Traditional medicines have their place, but plants play a vital role in drug development. Modern scientific techniques have helped verify the ancient knowledge of the healer. These traditional remedies incorporate many aspects of the body, including their chemical composition and their psychological effects. As a result, the study of traditional medicine is helping to discover future drug leads. Medicinal plants are used in many countries and have played a vital role in traditional healthcare systems for thousands of years. Today, about 50% of all drugs that are used in clinical practice are made from natural products.

Besides examining their properties, medicinal plants can also be used for cancer treatment. The research study documented the different plant species used in cancer management among Tswana speakers. The study also provided baseline data for further studies. Future studies will focus on the phytochemical and pharmacological profiles of these plants. The findings of this study have opened the door to further investigation into the effects of these plants on the human body. It also highlights the growing popularity of natural products.

Dietary supplements

The goal of dietary supplements for holistic health is to help people improve their health and well-being by addressing the root causes of the disease. Researchers and practitioners of holistic nutrition know that the body’s chemical processes are continuously occurring. They are affected by synthetic chemicals, which disrupt these processes. They also know that abnormal substances can interfere with decision-making and brain functions. Consequently, these substances may cause long-term damage. Instead of taking synthetic chemicals, holistic nutritionists recommend natural foods and herbal supplements.

A good source for dietary supplements is the Office of Dietary Supplements. This organization helps consumers find information on dietary supplements and answers questions about their efficacy. You can also contact the manufacturers to find out more about the supplement’s ingredients and efficacy. In addition, you can visit the National Center for Complementary and Integrative Health (NCCIH) or Office of Dietary Supplements, which have websites designed to help consumers make informed choices.

Some people have tried using dietary supplements for holistic health. However, their use is not recommended for everyone. These supplements are not meant to diagnose or treat diseases and are not as safe as medicines. However, they are effective in enhancing the current routine of a person. They are not a replacement for good eating habits. A healthy diet and exercise are important factors for holistic health. And you should not neglect your diet and your health if you want to see significant results from dietary supplements.

Alternative medicine

Holistic health is all about using the correct methods to achieve optimal health. Alternative medicine attempts to achieve the same effects as medicine, but is not scientifically proven. It has no biological plausibility and has been proven ineffective. Nonetheless, many people swear by it and use it for a wide variety of conditions. Below are some common examples of complementary and alternative medicine. Read on to learn more about the benefits and limitations of alternative medicine.

A holistic philosophy views the mind, body, and spirit as one. A dysfunction in one area affects the whole person. Complementary medicine is guided by this philosophy. Many Australians seek out alternative medicine after feeling dissatisfied with conventional medical care. They don’t believe in the harsh side effects of conventional drugs. It may be more gentle and safer. In addition, it involves a collaborative approach with both the patient and provider.

The holistic health care provider may prescribe medicines and surgical procedures to treat acute or chronic pain, or recommend exercise to boost the production of endorphins. Regardless of the condition, a holistic health care provider may also ask about your diet and lifestyle, identifying foods that contribute to inflammation and stress. If you suffer from pain, your holistic health care provider may recommend acupuncture or massage therapy, or even mindful meditation to relieve tension and stress.

Dengue Fever: Symptoms, Treatment, Vaccine, Rash, Causes & Contagious

Dengue fever is a mosquito borne illness that can cause symptoms such as muscle pain, headache, fever, and rash.
Dengue fever is a mosquito borne illness that can cause symptoms such as muscle pain, headache, fever, and rash.Source: MedicineNet

Dengue fever facts

  • Dengue fever is a disease caused by a family of viruses transmitted by Aedes mosquitoes.
  • Symptoms of dengue fever include severe joint and muscle pain, swollen lymph nodes, headache, fever, exhaustion, and rash. The presence of fever, rash, and headache (the "dengue triad") is characteristic of dengue fever.
  • Dengue virus is prevalent throughout the tropics and subtropics.
  • A virus causes dengue fever, and there is no specific medicine or antibiotic to treat it. For typical dengue fever, the treatment is directed toward relief of the symptoms (symptomatic treatment).
  • Papaya leaf extract can treat dengue fever.
  • The acute phase of the illness with fever and muscle pain lasts about one to two weeks.
  • Dengue hemorrhagic fever (DHF) is a specific syndrome that tends to affect children under 10 years of age. This complication of dengue causes abdominal pain, hemorrhage (bleeding), and circulatory collapse (shock).
  • The prevention of dengue fever requires control or eradication of the mosquitoes carrying the virus that causes dengue.
  • The U.S. FDA approved Dengvaxia, a vaccine for dengue fever, in May 2019 for use in dengue-endemic areas.

Read about dengue fever symptoms and signs.

Dengue Symptoms and Signs

Primary symptoms of dengue appear three to 15 days after the mosquito bite and include the following:

  • high fever and severe headache,
  • with severe pain behind the eyes that is apparent when trying to move the eyes.

Other associated symptoms are:

  • joint pain,
  • muscle and bone pain,
  • rash,
  • and mild bleeding.

Many affected people complain of low back pain.

Read more about dengue fever symptoms and signs »

Dengue fever is caused by a mosquito-borne virus.
Dengue fever is a mosquito borne illness that can cause symptoms such as muscle pain, headache, fever, and rash.Source: “Dengue” by CDC per University of South Carolina Biomedical Sciences

What is dengue fever? What causes dengue fever?

Picture of Aedes albopictus mosquitoPicture of Aedes albopictus mosquito

Dengue fever is a disease caused by a family of viruses transmitted by infected mosquitoes. It is an acute illness of sudden onset that usually follows a benign course with symptoms such as headache, fever, exhaustion, severe muscle and joint pain, swollen lymph nodes (lymphadenopathy), and rash. The presence of fever, itchy rash, and headache (the "dengue triad") is characteristic of dengue. Other signs of dengue fever include bleeding gums, severe pain behind the eyes (retro-orbital), and red palms and soles.

Dengue (pronounced DENG-gay) can affect anyone but tends to be more severe in people with compromised immune systems. Because one of five serotypes of the dengue virus causes dengue fever, it is possible to get dengue fever multiple times. However, an attack of dengue produces immunity for a lifetime to that particular viral dengue serotype to which the patient was exposed.

Dengue goes by other names, including "breakbone fever" or "dandy fever." Victims of dengue often have contortions due to the intense pain in the joints, muscles, and bones, hence the name breakbone fever. Slaves in the West Indies who contracted dengue were said to have dandy fever because of their postures and gait.

Dengue hemorrhagic fever is a more severe form of the viral illness. Symptoms include headache, fever, rash, and evidence of bleeding (hemorrhage) in the body. Petechiae (small red spots or purple splotches or blisters under the skin), bleeding in the nose or gums, black stools, or easy bruising are all possible signs of hemorrhage. This form of dengue fever can be life threatening and can progress to the most severe form of the illness, dengue shock syndrome.

Dengue fever affects tropical areas around the world.
Dengue fever affects tropical areas around the world.Source: CDC

What geographic areas are at high risk for contracting dengue fever?

According to the Centers for Disease Control (CDC), the dengue virus is prevalent throughout the tropics and subtropics (subtropical areas). Outbreaks have occurred recently in the Caribbean, including Puerto Rico, the U.S. Virgin Islands, Cuba, and Central America. Cases have also been imported via tourists returning from areas with widespread dengue, including Tahiti, Singapore, the South Pacific, including the Philippines, Southeast Asia, the West Indies, India, and the Middle East (similar in distribution to the areas of the world that harbor malaria and yellow fever). Dengue is now the leading cause of acute febrile illness in U.S. travelers returning from the Caribbean, South America, and Asia.

  • From January to July 2017, Sri Lanka reported 80,732 cases of dengue fever, with 215 deaths.
  • New Delhi, India, reported an outbreak of dengue fever, with 1,872 testings positive for the illness in September 2015.
  • In American Samoa, there were 370 cases of dengue reported from May 2015 to Sept. 2, 2015, and 133 were hospitalized.
  • Thailand reported the worst dengue virus outbreak in 20 years, with 126 deaths and 135,344 people infected with the virus, in October 2013.
  • In 2011, Bolivia, Brazil, Columbia, Costa Rica, El Salvador, Honduras, Mexico, Peru, Puerto Rico, and Venezuela reported a large number of dengue cases. Paraguay reported a dengue fever outbreak in 2011, the worst since 2007. Hospitals were overcrowded, and patients had elective surgeries canceled due to the outbreak.

The virus that causes dengue fever is transmitted to a person through an Aedes mosquito bite.
The virus that causes dengue fever is transmitted to a person through an Aedes mosquito bite.Source: MedicineNet

How do people contract dengue fever? Is dengue fever contagious?

The vector-borne dengue virus infection spreads via the bite of a striped Aedes aegypti and Aedes albopictus mosquito that has previously bitten an infected person. The mosquito flourishes during rainy seasons but can breed in water-filled flowerpots, plastic bags, and cans year-round. One mosquito bite can cause the disease.

The virus is not contagious and cannot spread directly from person to person. It is mosquito-borne, so there must be a person-to-mosquito-to-another-person pathway. A mosquito bites a dengue-infected person and becomes infected with dengue. That mosquito then bites another person and passes the dengue virus infection to that person. The full life cycle of the virus involves the Aedes mosquito as the vector (transmitter) and the human as the source of infection.

Avoiding mosquitos is important to avoid contracting dengue fever. In dengue-endemic tropical and sub-tropical areas, you should wear light-colored long-sleeved shirts and long pants or trousers, use insect repellant, stay or sleep indoors in air conditioning when possible and use mosquito netting over the bed if available.

Dengue is not a tick-borne illness. Only the bite of an infected mosquito can transmit dengue.

What is the incubation period for dengue fever?

After being bitten by a mosquito carrying the virus, the incubation period for dengue fever ranges from 3 to 15 (usually 5 to 8) days before the signs and symptoms of dengue appear in stages.




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Fever, rash, and headaches are the most common symptoms and signs of dengue fever.
Fever, rash, and headaches are the most common symptoms and signs of dengue fever.Source: Getty Images

What are dengue fever symptoms and signs?

Dengue fever starts with non-specific flu-like symptoms of chills, headache, pain in the back of the eyes that may worsen upon moving the eyes, appetite loss, feeling unwell (malaise), and low backache.

  • Painful aching in the legs and joints occurs during the first hours of illness.
  • The temperature rises quickly as high as 104 F (40 C), with relatively low heart rate (bradycardia) and
  • low blood pressure (hypotension).
  • The eyes redden.
  • A flushing or pale pink rash comes over the face and then disappears.
  • The lymph nodes in the neck and groin are often swollen.
  • High fever and other signs of dengue last for 2 to 4 days, followed by a rapid drop in body temperature (defervescence) with profuse sweating.
  • This precedes a period with normal temperature and a sense of well-being that lasts about a day.
  • A second rapid rise in temperature follows.
  • A characteristic itchy rash (small red spots, called petechiae) appears along with the fever and spreads from the extremities to cover the entire body except for the face.
  • The palms and soles may be bright red and swollen.

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A medical professional diagnoses a dengue fever patient.
Health care professionals may use a blood test called the DENV Detect IgM Capture ELISA to diagnose people with dengue fever.Source: Getty Images

What tests do health care providers use to diagnose dengue fever?

Medical professionals usually make a diagnosis of dengue fever infection when a patient exhibits the typical clinical symptoms and signs of headache, high fever, eye pain, severe muscle aches, and petechial rash and has a history of being in an area where dengue fever is endemic. Dengue fever can be difficult to diagnose because its symptoms overlap with those of many other viral illnesses and tropical diseases, such as the West Nile virus and chikungunya fever.

Health care professionals may use a blood test called the DENV Detect IgM Capture ELISA to diagnose people with dengue fever. The FDA notes that the test may also give a positive result when a person has a closely related virus, such as West Nile disease.

Rest and drinking fluids are home remedies for dengue fever.
Rest and drinking fluids are effective home remedies for dengue fever.Source: OJO Images/Getty Images

What is the treatment for dengue fever?

Because a virus causes dengue fever, there are no specific antibiotics to treat it. Antiviral medications are also not indicated for dengue fever. For typical dengue, the treatment is concerned with the relief of the symptoms and signs. Home remedies such as rest and fluid intake (oral rehydration) are important. Only take pain relievers such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) under a doctor's supervision because of the possibility of worsening bleeding complications. Acetaminophen (Tylenol) and codeine may be given for severe headaches and for joint and muscle pain (myalgia).

Patients hospitalized for dengue may receive IV fluids.

In several clinical studies, researchers proved that Carica papaya leaf extract (papaya leaf) is an effective treatment for dengue fever.

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Dengue fever is often treated with pain relievers and fluids.
Dengue fever is often treated with pain relievers and fluids.Source: Getty Images

What types of doctors treat dengue fever?

A primary care provider (PCP), such as your family practitioner or internist, can treat your dengue fever symptoms. A pediatrician can treat your child. If symptoms are severe, you may see an emergency medicine doctor in a hospital emergency department.

If your doctor is not familiar with treating dengue fever or your symptoms are severe, you may see an infectious disease specialist or a travel medicine physician.

How long does dengue fever last?

The acute phase of dengue with fever and muscle pain (myalgia) lasts about one to two weeks. A feeling of weakness (asthenia) and fatigue accompany convalescence, and full recovery often takes several weeks.

What is the prognosis for typical dengue fever?

The prognosis for dengue is usually good. The worst symptoms of the illness typically last 1 to 2 weeks, and most patients will fully recover within several additional weeks.

Typical dengue infection is fatal in less than 1% of cases; however, the more severe dengue hemorrhagic fever is fatal in 2.5% of cases. If dengue hemorrhagic fever is not treated, mortality (death) rates can be as high as 20%-50%.

Children are at greater risk for dengue hemorrhagic fever.
Children are at greater risk for dengue hemorrhagic fever.Source: iStock

What is dengue hemorrhagic fever?

Dengue hemorrhagic fever (DHF or dengue hemorrhagic fever) is a specific syndrome that tends to affect children under 10 years of age. This complication of severe dengue fever causes abdominal pain, hemorrhage (bleeding), and circulatory collapse (shock). DHF is also called Philippine, Thai, or Southeast Asian hemorrhagic fever or dengue shock syndrome.

DHF starts abruptly with continuous high fever and headache. There are respiratory and intestinal symptoms with a sore throat, cough, nausea, vomiting, and abdominal pain. Shock occurs 2 to 6 days after the start of symptoms with sudden collapse, cool, clammy extremities (the trunk is often warm), weak pulse, and blueness around the mouth (circumoral cyanosis).

In DHF, there is bleeding with easy bruising, red or purple blood spots in the skin (petechiae), spitting up blood (hematemesis), blood in the stool (melena), bleeding gums, and nosebleeds (epistaxis). Pneumonia is common, and inflammation of the heart (myocarditis) may be present.

People must closely monitor patients with DHF for the first few days since shock may occur or recur precipitously (dengue shock syndrome). Medical professionals will give cyanotic (having a bluish coloration to the skin and mucus membranes) patients oxygen. Vascular collapse (shock) requires immediate fluid replacement. Blood transfusions can control bleeding.

The mortality (death) rate with DHF is significant. With proper treatment, the World Health Organization estimates a 2.5% mortality rate. However, without proper treatment, the mortality rate rises to 20%. Most deaths occur in children. Infants under 1 year of age are especially at risk of dying from DHF.

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Controlling mosquito populations in urban areas could help reduce the number of dengue fever infections.
Controlling mosquito populations in urban areas could help reduce the number of dengue fever infections. Dengvaxia vaccine can be administered as a three-dose series in people 9-45 years of age.Source: Getty Images

Is it possible to prevent dengue fever with a vaccine?

In April 2016, the WHO approved Sanofi Pasteur's Dengvaxia (CYD-TDV), a live recombinant tetravalent vaccine for dengue fever. Dengvaxia can be administered as a three-dose series in people 9-45 years of age who live in areas where dengue is endemic.

In clinical trials in Latin America and Asia involving more than 40,000 children and adolescents, Dengvaxia protected 66% of people aged 9 and older against dengue. Dengvaxia was very effective at protecting against severe dengue, which can be fatal, preventing 93% of severe cases, and reducing hospitalizations due to dengue by 80%.

Health officials initially approved Dengvaxia in 2015 for use only in Mexico, the Philippines, Brazil, and El Salvador. In May 2019, the U.S. Food and Drug Administration approved the use of Dengvaxia for the prevention of dengue caused by all dengue virus serotypes (DENV-1, DENV-2, DENV-3, and DENV-4 — sometimes also referred to as DEN-1, DEN-2, DEN-3, and DEN-4) in people ages 9 through 16 who have laboratory-confirmed previous dengue infection and who live in endemic areas. In the U.S., dengue is endemic in the territories of American Samoa, Guam, Puerto Rico, and the U.S. Virgin Islands.

Several other vaccines for dengue are undergoing clinical trials, but none have yet been approved for use.

Where can people get more information on dengue fever?

"Dengue," Centers for Disease Control and Prevention
http://www.cdc.gov/Dengue/

Travel Medicine: Travel Vaccines, Cholera, Malaria & Other Risks

Why should travelers see a physician before they leave on a trip?

Travelers should see a physician before leaving for a trip if

  • they are going to developing countries,
  • they are visiting sites that are not on the usual tourist routes or traveling to high altitudes,
  • they have chronic diseases that could be affected by travel,
  • they are visiting countries that require vaccinations before they allow travelers to enter the country.

The goal of a pre-travel medical evaluation is to help travelers protect themselves against (1) common diseases that may be mild but that will disrupt their trip and (2) less common diseases that may be serious or even fatal. All travelers need to be up to date on routine vaccines they would normally get if they were not traveling. For example, an annual influenza vaccination (flu shot) is recommended if traveling during influenza season. Travelers should also be up to date on tetanus vaccines. If a tetanus booster is needed,
a physician may elect to use the Tdap vaccine that also provides continuing protect against adult pertussis. No immunizations are required for re-entry into the United States after travel. Some countries require you to provide an International Certificate of Vaccination or Prophylaxis prior to allowing border entry from certain countries, even if you are only stopping there to change planes, whether you are traveling to your destination or coming home.

What diseases occur in travelers, and how can disease be prevented?

Travelers can pick up infectious diseases from contaminated food or water, from insect bites, animal bites, or from other people. Immunizations, medications, and simple precautions can reduce or eliminate the risk of many of these travel-related infections. While infectious disease is the most common concern for travelers, it is important to remember that the most common cause of death in travelers is motor-vehicle accidents. Be sure to look both ways before crossing the street, review traffic laws (especially in countries where people drive on the opposite side of the road), don’t get in a car with a driver who is drunk, and use seat belts and infant/child car seats if available both at home and when traveling.

This review will cover infectious diseases commonly encountered by travelers or those for which vaccinations are recommended. For a more complete discussion of what may be need for travel to specific destinations and specific situations, please refer to the U.S. Centers for Disease Control and Prevention (CDC) Traveler‘s Health web site (http://wwwnc.cdc.gov/travel/).

Healthcare When Traveling Abroad

Many international travelers may be surprised to learn that they have no health insurance coverage for illnesses or injuries that must be treated during their trip abroad. In particular, the U.S. Social Security Medicare program does not provide any coverage for hospital or medical costs incurred outside of the United States. Individual health insurance policies vary in the amount, if any, of the costs they will reimburse for medical services in other countries.

Get more tips on healthy travel »

Traveler’s diarrhea

Traveler’s diarrhea is the most common medical complaint in travelers, occurring in up to 50% of travelers to developing countries. It occurs when infectious organisms are inadvertently ingested by travelers, resulting in one to five days of loose stools. The stools are often watery and may be accompanied by abdominal cramps. Although not fatal, traveler’s diarrhea can cause dehydration, vomiting, low-grade fever, and discomfort to the point that some travelers have to change their itineraries. It is important to note that traveler’s diarrhea is not associated with bloody stools, severe abdominal pain, or high fever. These symptoms are suggestive of more serious conditions and should prompt medical attention.

Traveler’s diarrhea is spread when bacteria or other infectious agents such as viruses are ingested. Traveler’s diarrhea is most often spread through contaminated food or water, or by putting contaminated hands in the mouth. Even small amounts of contamination can cause infection. Although bacteria are the most common cause of traveler’s diarrhea, there have been outbreaks of diarrhea on cruise ships caused by viruses known as noroviruses. Noroviruses spread readily from person to person.

Travelers can get diarrhea in most areas of the world, but some countries pose a higher risk. High-risk areas include most of Asia, the Middle East, Africa, and Central and South America. Risk is increased if the traveler is adventurous with his or her diet, eats foods from street vendors, or travels to areas off the usual tourist routes.

Protective measures may help prevent or shorten the duration of traveler’s diarrhea. All travelers should wash their hands often and understand basic food and water precautions (see “What is safe to eat and drink while traveling?”). However, it has been shown that even well-informed travelers often choose to eat foods that pose an increased risk of traveler’s diarrhea. Therefore, travelers at risk should carry in their first-aid kit an antimotility agent such as loperamide (Imodium; Kaopectate II; Imodium A-D; Maalox Anti-Diarrheal Caplets; Pepto Diarrhea Cont) and start taking it if they get symptoms. Bismuth subsalicylate (Pepto-Bismol) is also helpful.

Because bacteria are developing resistance to many antibiotics, many older antibiotics do not work, and those prescribed currently may not be effective in the future. Antibiotics also have risks of their own and do not protect against viruses or parasites; therefore, routine prophylactic antibiotics are not recommended for most travelers. However, many physicians recommend that travelers carry along an antibiotic to take in case they get diarrhea. Fluoroquinolones, such as ciprofloxacin, levofloxacin, ofloxacin, or norfloxacin, are the most commonly prescribed antibiotic; azithromycin (Zithromax, Zmax) or rifaximin (Xifaxan) are alternatives. If an antimotility agent (a drug that reduces gastrointestinal motility) and an antibiotic are started at the first sign of diarrhea, symptoms may be shortened to only a few hours instead of a few days.

Physicians might prescribe daily antibiotics or daily bismuth subsalicylate to prevent diarrhea in people who are immunosuppressed, or when the purpose of a trip would be severely impacted if it were interrupted by diarrhea. This is not needed for most travelers, and bismuth subsalicylate may cause adverse effects in doses required for protection. Pregnant women and children need special advice because many of these drugs are not appropriate for them. Affected people should stay well hydrated with beverages that are sealed, treated with chlorine, boiled, or are otherwise known to be purified; in most cases, commercial sports drinks are adequate, but very sugary drinks can worsen diarrhea. If antibiotics are prescribed, fill the prescription before travel; if you must buy drugs during a trip to an area of the world with few drug regulations, avoid counterfeits by using a licensed pharmacy, asking the pharmacist about the ingredients, and checking the packaging for poor print quality or odd appearance; drugs should be in the manufacturer’s original packaging if at all possible.




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Malaria

Malaria is an infection caused by a protozoan that enters red blood cells and multiplies until the cells burst open. The broken cells release the young protozoa into the bloodstream where they infect more red blood cells. This release of young protozoa causes high fevers that can last for several hours, as well as anemia due to the destruction of red cells. The fever of malaria often comes and goes, coinciding with when the infected red cells burst open. With some types of malaria, the protozoa can hide in the liver and cause episodes of fever over many years. In serious cases, malaria can cause the kidneys to shut down, can infect the brain (cerebral malaria), or cause death.

Malaria is spread to people by mosquitoes. The mosquitoes bite between dusk and dawn. Malaria occurs in many tropical areas and a few areas that have a milder climate. Travelers to sub-Saharan Africa, South America, and Asia may be at risk for the disease. Some countries in Central America and the Caribbean also have malaria. Not every area of a country will be affected. The people who have lived all their lives in the area with malaria typically have some immunity, but travelers are at much higher risk for severe infection, especially with some types of malaria. Malaria is serious enough to see a doctor about possible preventive medication if your itinerary suggests you might be exposed. The CDC has a web page that tells where malaria occurs (http://wwwn.cdc.gov/travel/). Many public-health departments and some private travel clinics provide pre-travel evaluations. CDC also offers a “Find a Clinic” web page to help you find one (http://wwwnc.cdc.gov/travel/page/find-clinic). The American Society for Tropical Medicine and Hygiene also has a list of clinics that specialize in travel medicine (http://www.astmh.org/source/ClinicalDirectory/).You should visit these clinics at least
four to six weeks before you travel in case you need vaccines, but especially with malaria it is better to go later than not at all to avoid traveling unprotected.

Malaria can be prevented by avoiding mosquito bites (see “What can I do to avoid insect bites?”) and by taking preventive medications. Travelers who will be exposed to malaria should take medications starting before travel to the area and continuing for a time after they leave the area. Several different medicines are available. Some are taken only once a week, and others are taken daily. In some countries, malaria has become resistant to older medicines. Your physician or travel clinic will choose which medicine to use based on what countries you are visiting. Some medicines must be started
two weeks before departure, so you should plan to go to the doctor or travel clinic well in advance. It is very important to take every last dose of preventive medication that may be prescribed to take after you return home, especially with types of malaria that hide in the liver and can return months later.

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Meningitis and encephalitis

There are several causes of meningitis, an infection of the lining and fluid around the brain and spinal cord. Encephalitis means that the brain tissue itself is also infected. There are serious types of meningitis and encephalitis that are associated with travel and can be prevented.

Meningococcal meningitis is one of the most serious types associated with travel to certain areas. The cause is a bacterium called
Neisseria meningitidis. The disease can be quite severe or even fatal. The infection is spread from person to person by close contact through coughing or sneezing or other respiratory means.

Meningococcal meningitis occurs at low rates throughout the world, including the United States. However, some countries have high rates of disease and pose a special risk to travelers. This includes many countries in the “meningitis belt” of sub-Saharan Africa. Saudi Arabia has experienced outbreaks when pilgrims travel to religious sites.

There are two effective vaccines to prevent meningitis. The choice of vaccine depends on the age of the patient. The vaccines are synthetic (meaning that they do not contain live infectious agents). They should not be given to people who have previously had a neurological illness called Guillain-Barré syndrome. Meningitis immunizations
are now routinely recommended for adolescents and college freshmen in the United States. It is also recommended for travelers who are going to areas that have high rates of infection. Vaccination is required for pilgrims to religious sites in Saudi Arabia, and proof of vaccination (preferably an International Certificate of Vaccination) will be required at the border. The vaccination is effective for three to five years (depending on which of the two vaccines is given), after which revaccination may be recommended for travelers who travel to areas with high rates of infection.

There are several kinds of viral encephalitis that occur in various areas of the world, such as Japanese
encephalitis virus, which are spread by mosquito bites. They are fortunately rare, and most viral encephalitis is prevented by avoiding mosquito bites (see the section on insect precautions). Japanese
encephalitis virus is preventable by vaccine, and a doctor or travel clinic can advise if you will need it.

Meningitis and encephalitis caused by parasites (amoebae) is also a concern for travelers. Harmless amoebae are common in freshwater and plumbing all over the world.
Naegleria fowleri prefers hot springs, lakes, rivers, or any warm freshwater that is untreated for human use; it may grow in pipes and hot water tanks of homes and buildings as chlorine dissipates. If affected water with enough
Naegleria is inhaled, it may cause severe meningoencephalitis; death occurs in 97%-99% of cases. This type of meningitis is hard to diagnose, children are often affected, and effective treatment is still being studied. Prevention is very easy. If bathing in hot springs or bodies of fresh water with unknown chlorination during hot seasons, keep the head above water, hold the nose shut, or use nose clips. Avoid getting bath or hose water up the nose. If you rinse your sinuses, or practice religious nasal cleansing, tap water is safe if boiled for at least
one minute and left to cool. Other options include using chemical disinfectants, filters with an absolute pore size 1 micron or less, and distilled or sterile water. Drinking affected water cannot transmit
Naegleria, and it cannot live in saltwater.

Yellow fever

Yellow fever virus is a rare cause of illness in U.S. travelers, but it can be serious, and some countries require proof of vaccination before border entry. It is caused by a virus that attacks the liver. Symptoms start within
three to five days of infection. In many people, the disease is mild and goes away. About 15% of people will develop severe disease with liver failure, and up to half will die. Yellow fever is spread by the bite of a mosquito.

Yellow fever occurs in areas of sub-Saharan Africa, Central America, and South America. Not all countries in these areas have yellow fever. Even within a country, some areas may have yellow fever while others do not.

There is a very effective vaccine available to prevent yellow fever. It contains a live virus that has been modified (“attenuated”) to make it safer. Vaccine side effects are usually mild. Rarely (a few cases per million doses), the vaccine virus can spread and cause severe disease. Infants under 6 months old, and people with weak immune systems (for example, people with certain chronic diseases, and some people with HIV infection or cancer) should not receive the live vaccine. These people should consult with a doctor before traveling to an area where yellow fever occurs. For people 60 or over and pregnant or breastfeeding women, a doctor should carefully review the risks and benefits of the vaccine.

Vaccination is generally recommended for travelers who will be exposed to yellow fever with the above exceptions. The vaccine may be required for entry into some countries. Check the CDC web site to see if vaccination is required for your trip. If you get vaccinated, you should receive an International Certificate of Vaccination, signed and validated with the center’s stamp where the vaccine was given. If you cannot be vaccinated, a medical waiver can be given. Take the certificate and any waivers with you on your trip. You may need it to enter your destination country or get back home. This certificate is valid for 10 years, and some countries are starting to accept it as valid for life. Yellow fever vaccine is only given at authorized U.S. yellow fever vaccine clinics, so you will need to check well in advance. CDC can help you find a place to get yellow fever vaccine (http://wwwnc.cdc.gov/travel/yellow-fever-vaccination-clinics-search.aspx).

The first line of defense against illness transmitted by insects is prevention of bites (see “What can I do to avoid insect bites?”).

Hepatitis A

Hepatitis A is caused by a virus that infects the liver. People get sick two to six weeks after they get the virus. Symptoms include nausea, yellowing of the skin and eyes (jaundice), dark urine, pale stools, loss of appetite, and fatigue. The symptoms take two to six months to completely resolve. Unlike some other hepatitis viruses, hepatitis A does not cause chronic liver disease. In other words, once the person gets better, he or she is completely cured. Some infected people (especially children) are asymptomatic, meaning that they do not develop symptoms.

Hepatitis A is spread when human waste is mistakenly ingested. Even a small amount can cause disease, such as might occur by shaking hands with someone
with contaminated hands and then touching the mouth. Food preparers have transmitted disease by mistakenly contaminating food. It is also possible to get hepatitis A through sexual contact or contaminated needles or blood. Hepatitis A occurs throughout the world but is more common in developing countries.

There is an effective vaccine that is quite good at preventing hepatitis A. If you are traveling to a developing country, your doctor will probably recommend vaccination. In a few cases, if you will be traveling before the vaccine has time to take effect, your doctor might recommend a more temporary measure called gamma globulin instead of or in addition to the vaccine. Remember to follow food and water precautions (see “What is safe to eat and drink while traveling?”). The vaccine also requires a second dose
six to 12 months later for full protection (or two or three more doses if combined with hepatitis B vaccine), so you will to follow up with your doctor after coming home. However, hepatitis A vaccine is protective for at least 25 years.

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Typhoid fever

Typhoid fever is an infection caused by a bacterium called Salmonella typhi. Most people who get sick develop a headache, a very high fever (up to 103 F or 104 F), and fatigue. Nausea, abdominal pain, diarrhea, or constipation may also occur.

The disease spreads when infected human waste contaminates food or water or is otherwise ingested. Some people are able to carry the bacteria inside their body for a very long time (“carriers”), even after symptoms have disappeared. Carriers can get it again or spread it to other people. People who get sick may be given antibiotics by their doctor. In addition to the antibiotics, people should make sure they always wash their hands after toileting and before cooking, so that they don’t spread the disease to anyone else. Some occupations require proof that you no longer carry any typhoid bacteria before you may go back to work; a doctor may perform several cultures of your stool before clearing you for work.

Typhoid fever occurs in many areas around the world, especially Asia, Africa, and South America. A vaccine is available to reduce the risk of getting typhoid, and it lasts several years. Ask
a doctor or local public-health department about typhoid vaccination before you travel. Food and water precautions (see “What is safe to eat and drink while traveling?”) also reduce the risk of disease. The saying “Boil it, cook it, peel it, or forget it!” helps you remember how to prevent becoming sick with typhoid fever (and many other infections) while traveling.

Polio

Polio is a viral illness that can lead to severe neuromuscular problems. Polio is spread from person to person. Infected oral secretions and feces can cause disease. Many people have no symptoms, but some have neurological problems such as weakness and paralysis. Symptoms are especially severe if they involve the breathing muscles. Some people are left with permanent neurological disabilities such as paralysis of limbs or breathing muscles.

Thanks to a global public-health campaign, many countries no longer have polio. A few countries in Africa, South Asia, Southeast Asia, and the Middle East still have outbreaks. The list of infected countries is constantly changing, as some countries successfully eliminate the infection and others become reinfected. If there is international spread from a country within 12 months, the World Health Organization (WHO) may declare a public-health emergency and issue updated vaccine requirements for travelers staying in those countries longer than
four weeks. Proof of vaccination on an International Certificate of Vaccination or Prophylaxis may be required before leaving. Check the CDC web site (http://cdc.gov/travel) for an update to see if your itinerary includes any of these countries.

The inactivated polio vaccine is recommended if the traveler is going to an area where polio is still occurring. Unless special circumstances arise as above, a single lifetime booster dose in adulthood is sufficient if the traveler has received the usual vaccine series in childhood. If the traveler has not been fully vaccinated in the past (has not received all doses at recommended times), more doses may be needed.

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Cholera

Cholera is an infection caused by bacteria (Vibrio cholerae) that look like curved rods when viewed under the microscope. The bacteria attach to the lining of the intestines and secrete a toxin. The cholera toxin can causes the cells in the intestines to pour out life-threatening amounts of fluid. The excess water loss can lead to watery diarrhea, so severe that it is difficult to keep the body hydrated. The term “rice water” is often used to describe this diarrhea because of the appearance of small white flecks of mucus in liquid.

Cholera spreads when human waste contaminates water and food. Because it takes high numbers of bacteria to cause infection, the contamination usually has to be quite significant. For example, in areas of poor sanitation, cholera can be spread when the drinking water supply is contaminated by feces from people who are sick.

Cholera is most common in areas that have poor sanitation, with faulty sewage systems or contaminated drinking water. Asia, Africa, and Latin America have been affected for several decades. Cholera can be prevented by using proper sanitation and sewage treatment. Boiling, filtering, or chlorinating water can help to prevent the spread of cholera. Treatment is mainly oral rehydration with simple electrolyte solutions. There is no vaccine for cholera that is approved in the United States. Following food and water precautions is the first line of defense (see “What is safe to eat and drink while traveling?”).

Cholera is very rare in recreational travelers, but travelers providing humanitarian aid to underdeveloped areas, or areas were sanitation and water supply is disrupted by disaster, should be aware of the risk of cholera. Basic knowledge of hand hygiene, infection control measures, and correct sanitation procedures can avoid inadvertent spread of infections and keep aid workers healthy and able to help.

What about diseases for which there is no vaccine or preventive medication?

There are several diseases of concern for travelers for which there is no vaccine or medicine to prevent infection. Among these are some viral infections, sexually transmitted diseases, and parasitic infections.

Many viral infections can be spread by biting insects such as ticks or mosquitoes. These include serious infections like hemorrhagic fevers, viral infections that cause high fever, and bleeding. While epidemics have been rare, Ebola virus has spread in an unprecedented way in recent years, in certain areas of Africa and beyond. Ebola has been associated with eating wild-caught bats, monkeys, and other animals. Most travelers do not encounter these types of viral hemorrhagic fevers.

Dengue fever occurs throughout the world in tropical areas. Symptoms of dengue fever are high fever, severe headache and joint pain, and a drop in blood pressure; occasionally, bleeding (hemorrhage) can occur in people who are reinfected. Chikungunya fever is native to Africa and Asia but has rapidly spread into the Caribbean in the same areas as dengue. Spread by the same mosquitoes, it causes high fever, severe joint pain, and may be indistinguishable from dengue; fever resolves after a few days. Severe joint pain may last for several weeks, but it leaves no permanent joint damage. The key to preventing these infections is to follow insect precautions (see “What can I do to avoid insect bites?”).

Sexually transmitted diseases remain common and can be acquired anywhere in the world. HIV is a risk everywhere and remains incurable. Gonorrhea, chlamydia, and syphilis remain common. The only sure way to prevent disease is to abstain from sexual intercourse. Correct use of condoms will reduce risk as well as unintended pregnancy. HPV vaccines now available will reduce the risk of acquiring infection with the human papillomavirus virus that causes genital warts and cervical cancer.

Parasites occur in most areas of the world but are especially common in tropical and subtropical regions. Some are spread by eating contaminated food (see “What is safe to eat and drink while traveling?”), while others are spread by direct contact with infected water or soil. Most travelers do not get parasitic infections, but those who are going into rural areas of developing countries should ask their doctors about parasites they might encounter.

Infectious-disease outbreaks occur periodically, and officials may recommend additional precautions. Examples have included outbreaks of bovine spongiform encephalitis (mad cow disease) or severe acute respiratory syndrome (SARS). Travelers should check the CDC web site to obtain health and risk information specific to their destination country. CDC also has specific advice for special groups and situations (http://wwwnc.cdc.gov/travel/page/common-travel-health-topics).

What is safe to eat and drink while traveling?

  • The first line of defense against illness at home and abroad is good hand hygiene. Wash hands with soap and uncontaminated water. If water quality is unknown, use a hand sanitizer with at least 60% ethanol often and before eating or drinking.
  • In general, it is best not to drink tap water in a developing country.
  • Boiled water and drinks made from boiled water (tea) are usually safe.
  • Carbonated bottled water or sodas are usually safe. Uncarbonated bottled water may be safe, but even bottled water may be filled up from the local tap water source.
  • Iodine tablets or commercially available water filters may be used to purify water when camping.
  • Ice (including flavored shaved ice or popsicles) is not safe in areas where the water supply may be contaminated. Make ice from disinfected or bottled, sealed water.
  • Alcohol (beer, wine) is usually safe.
  • Fruits and vegetables washed in contaminated water may have a residue of bacteria. In general, wash in clean water and peel them yourself.
  • Hot, well-cooked foods are usually safe. Avoid runny eggs.
  • Avoid street vendor food.
  • Avoid salsas and salads made with raw ingredients.
  • Avoid unpasteurized dairy products.
  • Spices do not kill bacteria. Food can be so spicy that it burns your mouth and still cause traveler’s diarrhea or more serious diseases.
  • Foods that put the traveler at high risk for infection include undercooked meat or seafood and bush meat (wild game such as bats, monkeys, other jungle game).

What can I do to avoid insect bites?

  • Wear light, protective clothing.
  • Use insect repellents that contain DEET (most popular brand-name insect repellents in the United States contain DEET), or picaridin, IR3535, and some oil of lemon eucalyptus and para-menthane-diol products. Reapply according to directions. When using sunscreen, apply sunscreen first and then repellent.
  • If you are hiking, tuck your pant legs into your sock. Check yourself over for ticks at the end of the hike including all creases, navel, and scalp. Many species bite in the nymph stage and are very small. Removing them within 24 hours prevents most infections.
  • Use mosquito nets or window screens if they are available.
  • Products that contain permethrin (NIX, an insect repellent) are available to spray on your clothes or tent for added protection.

What should be in my travel first-aid kit or medicine kit?

  • Your kit should be packed in your carry-on luggage.
  • Prescription medications that you take at home
  • Medications that your doctor recommended to prevent travel-related illness,
    including malaria medications, if indicated
  • Over-the-counter medicines to treat minor illnesses (heartburn, headache, head cold, mild diarrhea, motion sickness, travel sickness)
  • Sunscreen, lotion to use to treat sunburn
  • Insect repellents
  • Alcohol based sanitizer with over 60% ethanol content
  • Bandages, tape, thermometer, and tweezers
  • Other items according to your itinerary. Adventure travelers who are far from medical help will need to consider additional items such as water purification tablets, commercial suture/syringe kits to be used by local health-care provider (ask your doctor for a letter on letterhead stationary prescribing its use), and other necessities.
  • Condoms, especially if there is a chance you may have sex with new partners
  • Women who get vaginal yeast infections should consider carrying along a treatment course (pills or vaginal products)

What are the medical concerns with jet lag?

Jet lag happens when travelers cross several time zones and disrupt their normal sleep-wake cycle.

To reduce the duration and the symptoms of jet lag, try to be outside when the sun is up. It may make for a very long (or short) first day, but it will help you adjust more quickly. Some travelers also try to change their sleep-wake habits before they leave.

Medicines are available that can promote sleep, but there are few studies on how well they work with jet lag. Zolpidem (Ambien) is a prescription sedative that promotes sleep. Another group of prescription drugs known as benzodiazepines also promotes sleep, but they may have more side effects, including temporary amnesia. Melatonin is a natural hormone available as an herbal preparation in the United States. Doses of approximately 5 mg have been shown to induce sleep. Melatonin is available over the counter.

What if I have a medical condition or a chronic disease?

Careful preparation will allow most travelers with medical conditions to have a safe and enjoyable trip. See your physician before traveling to be sure your understand how to manage your condition while traveling. In some cases, an exercise regimen may be recommended to get in shape before the trip. It is important to check with your health-insurance provider to determine what is covered in the destination country.

Travelers with diabetes may need to adjust their insulin-dosing schedule if they cross several time zones. Frequent monitoring of blood sugar (glucose) by finger stick is usually recommended. Remember to carry insulin in your carry-on baggage (otherwise it will freeze in the cargo hold). An identification bracelet showing that you have diabetes is also recommended. Carry a source of sugar in case your blood glucose drops. Remember that exercise may cause blood sugar to dip, so always carry your supplies on hikes, etc. Finally, keep up with your fluids. Hydration can help avoid complications if your blood sugar jumps.

Travelers with heart disease should carry a recent electrocardiogram and a list of all current medications. Medications should be kept in carry-on luggage. If you have a pacemaker, you should know the name of the company that made it and how to contact someone if it stops working. Travelers with unstable heart disease (unstable angina, severe heart failure, recent heart attack, or unstable heart rhythm) should delay travel until their condition is stable.

Travelers who have problems with their immune system due to active cancer, chemotherapy, or AIDS may encounter special problems. In general, vaccines made from live organisms are usually avoided in people with significantly impaired immune systems. Even non-live travel-appropriate vaccines may not work as well as usual, but they are still beneficial and should be given. Consider delaying travel until the immune system is back to normal, if this is possible. Consultation with a disease specialist and a travel-medicine specialist before departure is strongly recommended.

Blood clots may pose a risk to certain travelers, especially on long flights or periods of immobility. Discuss your risk with your doctor, and consider wearing compression or support stockings on your trip.

Travelers with disabilities should know that accommodations will vary widely between and within countries. The Department of Transportation can assist with getting accommodations on airplanes (1-800-778-4838). Service animals such as guide dogs are subject to quarantine regulations and may not be allowed to enter some countries.

A broad array of special situations and common travel health topics are addressed by CDC (http://wwwnc.cdc.gov/travel/page/common-travel-health-topics).

What if I’m traveling while pregnant?

Pregnant women should consult with their obstetrician before travel. If available, a consultation with a travel medicine clinic is also recommended. Live vaccines are usually avoided in pregnancy. An up to date flu shot is safe and important, because flu can be very serious in pregnancy, and flu circulates at different times throughout the world. Some medications must also be avoided. This may put pregnant women at higher risk for getting sick in a foreign country. Blood clots are also more likely during pregnancy, especially with prolonged immobility and air travel.

Pregnant women should also be aware that the quality of obstetrical care in foreign countries varies considerably. It is best to have the name of a reputable clinic or hospital on hand. Women in the third trimester should consider delaying travel until after delivery. Check with your health-insurance provider in advance to determine what is covered in the destination country. You may want to purchase medical travel insurance with evacuation services (See “Travel Health Insurance & Medical Evacuation Insurance”).

Diarrhea, some types of hepatitis, and malaria can be especially severe in pregnant women. Follow food, water, and insect precautions. Avoid areas with malaria if at all possible, and take medications as directed.

What about traveling with children?

Children should be up to date on all routine vaccinations including those for mumps, measles, rubella, polio, hepatitis B, tetanus, diphtheria, and varicella (chickenpox/shingles). Some vaccinations and medications are not recommended for children. This means that the risk or severity of certain diseases is increased in children.

Diarrhea is more common in children because so much ends up in their mouths. Children can quickly become dehydrated. Make sure that your child drinks plenty of fluids. Consider adding an oral rehydration solution to your medical kit.

Children are attracted to animals and are more likely to get bitten. Bite wounds may become infected or transmit rabies. Keep children away from animals.

Newborns and infants are at special risk because they are easily dehydrated and many vaccines and medications are contraindicated in this age group. Breastfeeding will help reduce the risk of diarrhea. There are limited options for malaria prevention in infants. Around the world, malaria remains one of the major causes of death in children.

Travel health insurance & medical evacuation insurance

Most health insurance policies have very limited coverage outside the home country, and your portion of the cost may be much more than it would be at home. Some may not cover travel-related care at all, or not cover emergencies related to high-risk activities. You may also be more comfortable with familiar health care in familiar surroundings, and being seriously ill away from home and family may can add an unanticipated and heavy financial burden, as well as psychological stress. Furthermore, most care will require up front cash or credit payment or not accept health insurance.

If you have a chronic disease, immune deficiency, or are pregnant in the third trimester, it may be especially beneficial, but anyone traveling outside the continental U.S. may wish to consider purchasing short-term travel health or medical evacuation insurance. This type of coverage is usually inexpensive compared to the cost of an unexpected health emergency. Most out of country health emergencies are related to motor-vehicle accidents and trauma, rather than health issues.

The U.S. Department of State can provide information on health care and medical emergencies when traveling abroad (http://www. travel.state.gov).

Travel safety and health alerts

Keep current on travel warnings and alerts related to crime, civil unrest, or terrorism by checking with the U.S. State Department for current
travel alerts and warnings (http://travel.state.gov/content/passports/english/alertswarnings.html).
Enrolling in the Smart Traveler Enrollment Program (STEP) with the U.S. Bureau of Consular Affairs Register your itinerary and contact information with the U.S. Consulate office at your destination (https://step.state.gov/step/).

Where can I find additional information?

  • The Centers for Disease Control and Prevention (CDC) has a web site that can give you details about travel-related illnesses and precautions specific to individual countries: http://www.cdc.gov/travel/. To contact the CDC by phone, call 877-FYI-TRIP.
  • CDC has a Find a Clinic web page to help you find a travel clinic: http://wwwnc.cdc.gov/travel/page/find-clinic.
  • CDC also has a web page to help you find a travel clinic that is also an authorized U.S. yellow fever vaccine center: http://wwwnc.cdc.gov/travel/yellow-fever-vaccination-clinics-search.aspx.
  • The American Society for Tropical Medicine and Hygiene has a list of clinics that specialize in travel medicine: http://www.astmh.org/source/ClinicalDirectory/.
  • Your doctor or the local public-health department will be able to help you manage chronic diseases abroad and get the vaccines and prescriptions you need.

SARS Symptoms, Causes, Treatment, Prevention & Transmission

Severe acute respiratory syndrome (SARS) facts

SARS causes a decrease in white blood cells and platelet (clotting cell) counts in the blood.SARS causes a decrease in white blood cells and platelet (clotting cell) counts in the blood.

  • SARS is the febrile "severe acute respiratory syndrome" that first appeared in 2003 and spread rapidly to more than two dozen countries across the world, infecting over 8,000 people and killing 774 before it could be contained in 2004.
  • SARS is caused by a coronavirus (SARS-CoV) that exists in bats and palm civets in Southern China.
  • This infection can be spread easily from close person-to-person contact (such as living in the same household) via respiratory droplets that come in contact with skin or mucous membranes (eyes, mouth, or nose).
  • Infected people become ill within a week of exposure. During the first week, nonspecific symptoms of a flu-like illness begin. This period is followed by a syndrome of "atypical" pneumonia, including dry cough, and progressively worsening shortness of breath with poor oxygenation.
  • Since these are nonspecific symptoms and findings, the diagnosis of SARS is only considered if the individual has also had specific risk factors within 10 days prior to illness.
  • If there are grounds for suspicion, respiratory secretions are sent for testing at the CDC.
  • There is no medication that is known to treat SARS. Treatment is supportive.
  • During the 2003 outbreak, approximately 25% of people had severe respiratory failure and 10% died.
  • The SARS outbreak in 2002-2003 was controlled solely by using public-health measures, such as wearing surgical masks, washing hands well, and isolating infected patients.
  • Two other coronavirus types are related to SARS, MERS and Wuhan coronavirus. They can cause severe infections in humans.

Cough is a symptoms of SARS.

SARS Symptoms & Signs

Severe acute respiratory syndrome (SARS) is a febrile illness that first appeared in 2003 and spread rapidly across the world from 2002-2003.

Signs and symptoms of SARS include flu-like nonspecific symptoms including fever, chills, and malaise. Symptoms develop within a week of infection with the virus. Infected people become ill within a week of exposure. The next associated symptoms include signs and symptoms of atypical pneumonia with respiratory distress, shortness of breath and dry cough.

Read more about SARS »

What is severe acute respiratory syndrome (SARS)?

SARS is an infectious respiratory illness caused by a coronavirus. The first cases of SARS occurred in late 2002 in the Guangdong Province of the People's Republic of China. Because of the contagious nature of the disease and the delayed public-health response, the epidemic spread rapidly around the globe. Final statistics from the World Health Organization showed 8,096 reported illnesses and 774 deaths.

The rapid transmission and high mortality rate (about 10%) of SARS drew international attention and concern. Fortunately, public-health efforts to identify and quarantine infected people proved highly effective. By July 2003, human-to-human transmission of SARS had stopped.

Unfortunately, future outbreaks of SARS are still possible because the virus lives in wild bats and civets in China and in laboratory cultures. In fact, there were a few human cases of SARS in 2004 as a result of laboratory accidents in the People's Republic of China. No human cases have been identified since.

The previously unknown coronavirus that causes this syndrome was first identified in Asia in early 2003, hence its name, "SARS-associated coronavirus" or SARS-CoV. As of October 2012, SARS-CoV has been added to the National Select Agent Registry, which regulates the handling and possession of bacteria, viruses, or toxins that have potential to pose a severe threat to public health and safety. The addition of SARS-CoV permits maintenance of a national database and inspection of entities that possess, use, or transfer SARS-CoV; it also ensures that all individuals who work with these agents undergo security-risk assessment performed by the Federal Bureau of Investigation/Criminal Justice Information Service.

Middle East respiratory syndrome coronavirus (MERS-CoV) is another coronavirus in humans that was identified in an outbreak in residents and travelers to the Arabian peninsula in 2012. It is not the same coronavirus as SARS-CoV, but it is similar to bat coronaviruses, and it is likely to have originated in animals as well. MERS-CoV is discussed in another article.

In late 2019, medical professionals noted yet another coronavirus outbreak. The new virus, Wuhan virus (also termed 2019-nCoV), an RNA virus related to both SARS and MERS coronaviruses, likely originated in infected animals marketed as food in Wuhan, China. The virus, like SARS, may cause moderate to severe respiratory problems in individuals and appears to spread from person to person. Most patients with the Wuhan virus require hospitalization. Within 1 month, the virus spread to at least 6 countries, including the U.S.




IMAGES

SARS
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What causes SARS? How is SARS transmitted?

SARS is caused by a virus referred to as "SARS-CoV" from the coronavirus genus; SARS-CoV means severe acute respiratory syndrome-associated coronavirus. Many coronaviruses infect animals and humans, and the common cold is caused by some coronaviruses
and several other viruses. SARS-CoV virus had never been identified before 2002. This was not entirely surprising because there are many types of coronaviruses, and they are known to mutate easily.

SARS-CoV likely originated in wild bats and then spread to palm civets or similar mammals. The virus then mutated and adapted itself in these animals until it eventually infected humans. There was ample opportunity for the virus to come into contact with humans. Bats serve as a food source in parts of Asia, and their feces are sometimes used in folk medicines. Civets are cat-like mammals that live in the tropics of Africa and Asia and produce musk from their scent glands, which is used in perfumes. Civets are also hunted for meat in some parts of the world. These animals could easily transmit the virus to humans.

SARS-CoV is spread from person to person through respiratory secretions. SARS often affected people caring for a sick individual and spread readily through health care facilities until infection-control measures were established. SARS-CoV was isolated from many hospital surface areas, including elevator buttons, likely contributing to the spread of the disease among healthcare workers. During the outbreak, one in about every 20 infected people was a health care worker who cared for a patient with SARS; nearly 2,000 health care workers became ill.

Is SARS contagious? How long is the contagious period for SARS?

SARS is contagious from person to person by droplets in respiratory secretions, such as during coughing or sneezing, much like the common cold. In addition, droplets on surfaces can be touched and rubbed into eyes, nose, or mouth membranes. Relatively close contact is required, such as being within 3 feet of a symptomatic person while living with them, sleeping in the same room, sharing household items with them, or providing medical care for them.

The contagious period is generally from the time symptoms start (end of the incubation period) and is greatest during the second week of symptoms. People with SARS should avoid leaving home until 10 days after symptoms end due to possible contagiousness.

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What is the incubation period for SARS?

The time between getting infected and the start of symptoms (the incubation period) is about
two to seven days but occasionally has been up to 14 days.

What are risk factors for SARS?

SARS-CoV can infect a person regardless of their health status or age group. However, it was clear that some people were at increased risk during the 2002-2003 outbreak. This included people over the age of 50 (some reported mortality rates of about 50%), pregnant women, and those with underlying diabetes, heart disease, or liver disease. A major risk factor is simply close association with any person infected with SARS-CoV since the virus can be spread through droplets sprayed into the air by coughing, sneezing, or even talking.

Other risk factors include the following:

  • Recent travel to mainland China, Hong Kong, or Taiwan or close contact with ill people
    with a history of recent travel to these areas
  • Employment in an occupation at risk for SARS-CoV exposure, including a health care worker with direct contact with a patient having SARS-CoV, or a worker in a laboratory that contains live SARS-CoV
  • Relationship with a cluster of cases of atypical pneumonia without an alternative diagnosis

What are SARS symptoms and signs?

Symptoms begin two to seven days after acquiring the virus. Initially, the illness resembles influenza and lasts for up to one week. Symptoms include fever, chills, headache,
aches or pain in the muscles, general feeling of weakness (malaise), and poor appetite. Nausea, vomiting and diarrhea are less common. This period is followed by a syndrome suggesting atypical pneumonia, including dry cough and progressively worsening to severe shortness of breath (dyspnea) and inability to maintain oxygenation (hypoxia). Progression may be rapid or it may take several days. Severely affected people develop a potentially fatal form of respiratory failure, known as adult respiratory distress syndrome (ARD or ARDS). In addition to the attacking the alveoli (air sacs) in the lungs, the virus also infects other organs in the body, causing kidney failure, inflammation of the heart sac (pericarditis), or severe systemic bleeding from disruption of clotting system (disseminated intravascular coagulation), reduced lymphocyte cell counts (lymphopenia), inflammation of the arteries (vasculitis), and inflammation of the gut with diarrhea. People with compromised immune systems such as severe rheumatoid arthritis or organ transplantation may not experience respiratory symptoms but can have fever or diarrhea.

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What kind of specialists treat SARS?

Most people with SARS would see a primary-care provider or an emergency-medicine doctor as illness rapidly progressed. Depending on
the stage of illness, they would be admitted to a hospital as oxygen levels decreased. In the hospital, a person with SARS would likely be managed by a hospitalist or critical-care doctor, with consultations to an infectious-disease doctor and
a lung doctor (pulmonologist).

How do health care professionals diagnose SARS?

SARS-CoV is detected using enzyme-linked immunoassays (EIA) or reverse transcriptase polymerase chain reaction (PCR) tests, which are available through the CDC. These tests are performed on respiratory secretions or blood.

These tests are performed only when the patient’s history makes SARS likely and usually in consultation with infectious-disease doctors, public-health authorities, and the Centers for Disease Control and Prevention. If a test is positive, it will be confirmed by the CDC. Other tests may be abnormal, but they are not specific for SARS. The chest X-ray shows pneumonia, which may look patchy at first. White blood cells and platelet (clotting cell) counts in the blood are usually decreased.

SARS should be considered in people with the appropriate symptoms who work with SARS-CoV in a laboratory or who have recent exposure to infected people or mammals in Southern China. No human cases of SARS have been reported since 2004 in the United States, so it is extremely unlikely that a patient in the U.S. will have SARS without a history of such exposure. It is possible, however, that a new outbreak might occur. Therefore, SARS
(along with other similar viruses) should also be considered when there is a
cluster of unusually severe pneumonia that has no other explanation.

What is the treatment for SARS?

Patients with SARS often require oxygen therapy, and severe cases require tracheal intubation and mechanical ventilation to support life until recovery begins. Severely ill patients should be admitted to the intensive-care unit. No medication has been proven to treat SARS effectively, and treatment is supportive and directed by the patient’s clinical condition. Medical caregivers need to follow strict policies on gloves, masks, gowns, and other protocols to avoid becoming infected.

What is the prognosis of SARS?

During the pandemic, approximately 25% of people with SARS developed severe respiratory failure or ARDS. In the general population, people with SARS had approximately a 10% chance of dying. Deaths in children were rare. However, up to 50% of people with underlying medical conditions died. People over 50 years old also had a similar death rate. Unfortunately, many people who eventually recovered from SARS in China suffered disabling lung scarring (pulmonary fibrosis), thinning of bones (osteoporosis), and severe damage to the hip bone (femoral head necrosis).

Is it possible to prevent SARS?

Travelers to affected areas can protect themselves by taking simple measures that help prevent the spread of germs. Frequent hand washing with soap and water, or using an alcohol-based hand sanitizer, avoiding close contact with sick people, and not touching one's eyes, nose, and mouth can prevent the spread of viruses.

The SARS pandemic was brought to an end by basic public-health and infection-control measures. In the health care setting, someone with a suspected case of SARS is placed in an airborne infection isolation room (AIIR). This is a patient care room used to isolate people with suspected or confirmed airborne infectious diseases. The air is under negative pressure, meaning that contaminated air is continually sucked into the room instead of letting it leak out into the hospital environment. This air is exhausted outside, or it circulates back into the room after passing through a high-efficiency particulate air (HEPA) filter to decontaminate it. If an AIIR not available, the patient must wear a face mask and is isolated in a single-patient room with the door closed. The number of staff assigned and the patient's movements outside of the room must be minimized. Before entering the isolation room, health care workers caring for the patient must wear a gown, gloves, eye shield, and mask or a portable air purifier that filters out small infectious particles (N95 mask). Before leaving the room, any disposable gear such as gowns, gloves, and mask must be discarded. Hands must be cleansed with soap and water or an alcohol-based hand sanitizer after leaving the room and before attending to another patient.

Most public-health officials recommend isolation for anyone diagnosed with SARS-CoV.

The key to preventing another outbreak is to identify the first infected patients promptly before they have time to spread the illness more widely. People who have been exposed to an infected individual should be carefully monitored for fever or respiratory symptoms. Exposure is defined as living with or caring for an infected person, being within 3 feet of the sick person, exposure to bodily fluids, or direct physical contact. The Centers for Disease Control and Prevention does not mandate quarantine measures for exposed individuals who are otherwise healthy and allows this decision to be handled on a case-by-case basis. Local public-health authorities should be consulted promptly when the diagnosis is suspected. If a significant outbreak of SARS occurs again, people may be advised to maintain a distance from others in the community ("social distancing") by avoiding large gatherings or close contact with others. However, isolation and quarantine methods have been effective in the prevention of SARS spread.

Is there a SARS vaccine? What research is being done on SARS?

Research on a vaccine continues, but none is available yet. Most research is examining the virus itself and chemical pathways that may pose opportunities for drugs to treat it.

Where can people get more information about SARS?

Information on SARS may be obtained from the CDC
or the World Health Organization: http://www.who.int/csr/sars/en/.

Malaria Symptoms, Treatment, Causes, Types, Contagious & Prevention

Malaria facts

 Picture of Malaria Precautions

Picture of Malaria Precautions by Sleeping Under Mosquito Nets Treated with Insecticide

  • More than 215 million cases of malaria occurred worldwide in 2016.
  • The World Health Organization estimates that 445,000 people died of malaria in 2016; the vast majority are young children in sub-Saharan Africa.
  • Although this is a significant decrease in deaths since 2000 due to increased prevention and control measures, there has been an increase from 2015 to 2016.
  • Health care professionals diagnose about 1,700 people with malaria in the U.S. each year, usually in travelers returning from endemic areas.
  • Malaria was a serious public health threat in the U.S. until disease-control programs eliminated it during the 1920s-1940s. Much of the early work done by the CDC focused on controlling and eliminating malaria in the U.S.

What is malaria?

Malaria is a serious, life-threatening, and sometimes fatal, disease spread by mosquitoes and caused by a parasite. Malaria was a significant health risk in the U.S. until it was eliminated by multiple disease-control programs in the late 1940s. The illness presents with flu-like symptoms that include high fever and chills.

There are three necessary aspects to the malaria life cycle:

  1. The Anopheles mosquito carries the parasite and is where the parasite starts its life cycle.
  2. The parasite (Plasmodium) has multiple subspecies, each causing a different severity of symptoms and responding to different treatments.
  3. The parasite first travels to a human's liver to grow and multiply. It then travels in the bloodstream and infects and destroys red blood cells.

Learn how to prevent malaria when traveling abroad.

Malaria Prevention

Many travelers to tropical countries are concerned about the possibility of contracting malaria, a potentially fatal infection transmitted by the bite of a female Anopheles mosquito. While malaria is most common in Africa, the disease occurs in over 100 countries.

Learn more about malaria prevention »

Is malaria contagious?

Malaria is a mosquito-borne disease and that does not spread from person to person (except in pregnancy as noted below) but spreads in certain circumstances without a mosquito. This occurs rarely and is usually found in a transmission from a pregnant woman to an unborn child (congenital malaria), by blood transfusions, or when intravenous-drug users share needles. Except for the above conditions, malaria is not considered contagious person to person.

What is the incubation period for malaria?

Following the mosquito bite, there is about a seven- to 30-day period before symptoms appear (incubation period). The incubation period for P. vivax is usually 10-17 days but can be much longer (about one year and rarely, as long as 30 years!). P. falciparum usually has a short incubation period (10-14 days). Other species of Plasmodium that cause malaria have incubation periods similar to P. vivax.

What causes malaria? What are the types of malaria?

Parasites of the genus Plasmodium cause malaria. Although there are many species of the malaria parasite Plasmodium, only five infect humans and cause malaria.

Plasmodium falciparum: found in tropical and subtropical areas; major contributor to deaths from severe malaria

P. vivax: found in Asia and Latin America; has a dormant stage that can cause relapses

P. ovale: found in Africa and the Pacific islands

P. malariae: worldwide; can cause a chronic infection

P. knowlesi: found throughout Southeast Asia; can rapidly progress from an uncomplicated case to a severe malaria infection




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What are malaria symptoms and signs?

Malaria has a wide spectrum of symptoms. After the bite by the infected mosquito occurs, it can take between seven and 30 days (average is seven to 15 days) before symptoms start (incubation period).

Health care professionals classify malaria as uncomplicated or complicated (severe).

Uncomplicated malaria

The most common symptoms are

The classic description of a malaria attack (which is rarely observed), would be a six- to 12-hour period of cold and shivering alternating with fever and headaches and then a stage of sweating and tiredness (sometimes divided into the cold and hot stage).

As these symptoms are very nonspecific, it is important to evaluate if the patient has risk factors for malaria (usual travel in endemic areas).

Complicated or severe malaria

This occurs when malaria affects different body systems.

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What specialists treat malaria?

Malaria can be treated by your primary care doctor (pediatrician, family medicine, internal medicine), as well as by infectious-disease specialists.

How do physicians diagnose malaria?

The symptoms of malaria can mimic many other diseases, including influenza or a viral syndrome. It is therefore important to inquire about a history of recent travel to an endemic area or other possible exposures.

Physicians make a definite diagnosis of malaria by looking at the blood of an infected patient under the microscope (blood smear) and identifying the presence of the parasite. The patients' blood is prepared under a slide with a specific stain to help identify the parasite. This is the most widely performed and accepted test.

Rapid diagnostic tests (antigen tests) are available that can give the diagnosis in a few minutes. It is recommended that a blood smear examination follows a positive test.

What is the treatment for malaria?

Besides supportive care, the medical team needs to decide on the appropriate antimalarial drug(s) to treat malaria. The choice will depend on several factors, including

  • the specific species of parasite identified,
  • the severity of symptoms, and
  • determination of drug resistance based on the geographic area where the patient traveled.

Physicians will administer the medication in pill form or as an intravenous antimalarial depending on above factors.

The most commonly used medications are

Can malaria reoccur after treatment?

P. vivax and P. ovale can hibernate in the liver and cause relapsing disease weeks or months after the patient is symptom free.

The FDA approved tafenoquine (Krintafel) as a medication to prevent relapses of Plasmodium vivax in patients 16 years of age and older. It is a single-dose medication that will provide a significant new tool in fighting P. vivax malaria relapse, according to researchers.

What is the prognosis of malaria?

If diagnosed early and if the appropriate antimalarials are available and used, the prognosis of malaria is very good.

Worldwide, malaria is responsible for over 400,000 deaths per year. The majority of victims are young children from sub-Saharan Africa. Death is usually due to lack of available treatment or access to treatment.

P. falciparum tends to be the species causing the most complications and has a high mortality if untreated.

Cerebral malaria, a complication of P. falciparum malaria, has a 20% mortality rate even if treated.

Is there a malaria vaccine?

There is currently no commercial vaccine available to prevent malaria. Due to the diversity of the Plasmodium species and the P. falciparum species being the deadliest parasite, most efforts are currently directed toward a P. falciparum vaccine. RTS,S/ASO1 is the most advanced candidate as a viable vaccine.

A phase 3 trial of RTS,S/ASO1 was completed and results published in 2015. The WHO is supporting the pilot implementation in several sub-Saharan countries.

How can people prevent malaria?

The prevention of malaria includes several steps.

First, evaluate if malaria is a concern in the area of travel (CDC malaria information by country table). This table will also indicate which medication to take as chemo-prophylaxis.

If chemo-prophylaxis is recommended, discuss the recommended medications with a health care professional to determine if they are appropriate. Take into consideration any medical conditions, drug interactions with current medication taken on a continual basis, as well as side effects of the recommended medications.

No medication is 100% effective, and therefore the prevention of mosquito bites is of paramount importance. These preventive measures should include the following:

  • Sleeping under bed nets: These should cover all of the bed down to the floor. These nets are most effective when treated with an insecticide.
  • Clothing: Clothing that covers most of the exposed skin and shoes that are closed can reduce the risk of bites. Tuck in all clothing, and pants should be tucked into socks to avoid exposure around the ankles. In addition, treating clothes with insecticides can prevent bites even further.
  • Apply insect repellent to all exposed skin.

Leptospirosis Vaccine, Symptoms, Treatment & Diagnosis

Facts you should know about leptospirosis

  • Leptospirosis is an infectious disease that can occur in humans and animals worldwide.
  • A type of spiral-shaped bacterium called a spirochete, Leptospira interrogans, causes leptospirosis.
  • High risk factors for leptospirosis include close association with animals and the water and soil they may contaminate with infected urine.
  • Symptoms and signs of leptospirosis are highly variable and range from no symptoms to nonspecific symptoms including
    • high fever,
    • chills,
    • headache, and
    • abdominal symptoms to Weil's disease with organ dysfunction.
  • Diagnosis of leptospirosis is done by isolating the bacteria from the patient. Blood tests are also available.
  • There are antibiotics that are effective in treating leptospirosis.
  • Most people infected with Leptospira interrogans bacteria have a good prognosis; a few have a more guarded prognosis.
  • Vaccines are available for humans and animals in some countries. There is no vaccine available commercially for humans in the U.S. Available vaccines are limited because they usually only protect well against a single serovar. Doxycycline (Vibramycin, Oracea, Adoxa, Atridox) has been used as a short-term preventive treatment to protect some humans from leptospirosis.

Leptospirosis Symptoms

Muscle Pain

Muscle pain originates in any of the muscles in the body. The medical term for muscle pain is myalgia. Muscle pain may arise due to injury or overexertion, infections of the soft tissues, or inflammatory conditions. A number of conditions can be associated with generalized aches and pain, such as influenza, that are perceived to be muscle pain. Muscle pain can be localized to one muscle group or diffuse, involving multiple muscle groups.

Learn more about causes of muscle pain »

What is leptospirosis?

Leptospirosis (also known as Weil's disease, grippotyphosa, and canicola) is a disease caused by bacteria (Leptospira interrogans) that produce a wide range of symptoms that may occur in two phases; some patients may develop kidney or liver failure, respiratory failure, meningitis, or even death. The bacterial infection is spread by the urine of infected animals from many species, both domesticated (such as dogs and horses) and wild infected animals (such as rodents or wild pigs). It is termed a zoonotic disease or a zoonosis because it occurs in wild animals. The bacteria can survive in freshwater and soil for months. The disease is most common in temperate and tropical climates. The infecting bacteria occur worldwide (for example, in the United States, Leptospira has been found in Hawaii's freshwater ponds and waterfalls).

What causes leptospirosis?

The cause of leptospirosis is bacteria (genus Leptospira and species interrogans), a Gram-negative spirochete (spiral-shaped bacteria). The Leptospira bacteria infect many types of animals (many wild animals, rodents, dogs, cats, pigs, horses, cattle, for example) that subsequently contaminate water, lakes, rivers, soil, and crops when they urinate because the bacteria are present in urine. The bacteria then infect humans when they invade through breaks in the skin or mucus membranes or when people ingest them. The bacteria multiply in the liver, kidneys, and central nervous system. Person-to-person transfer of this disease is rare.

Is leptospirosis contagious? What is the contagious period for leptospirosis?

In general, human leptospirosis is considered weakly contagious. This is because, like other animals, humans can shed leptospirosis in the urine during and after illness. Consequently, individuals exposed to the urine of humans who are infected may become infected. For example, although the bacteria are not airborne and have a low risk of being in saliva, individuals handling wet bedding or blood-soaked material from an infected person can increase the chances of getting the infection. There are a few reports of transmission between sexual partners, but the incidence of this type of spread seems very low. Unfortunately, pregnant mothers who get leptospirosis can infect their fetus.

The contagious period for leptospirosis depends on how long viable organisms are shed in the urine. Most individuals will shed organisms in the urine for a few weeks but there are reports that humans can continue to shed the organisms in urine for as long as 11 months. Some experts suggest that there is risk for up to 12 months after getting the initial infection.

What is the incubation period for leptospirosis?

The incubation period for leptospirosis is approximately seven to 12 days but it may range from two to 30 days.

What are risk factors for leptospirosis?

Risk factors include occupational exposure in people to with farm animals, wild animals, and to contaminated water and soil (farmers, slaughterhouse workers, veterinarians, miners, military personnel, disaster workers and victims, for example). People who participate in outdoor activities such as camping or kayaking are also at higher risk for infection. Any exposure to sewage or animal waste, including stools from infected dogs, increases the risk of getting leptospirosis. Heavy rainfall may cause the bacterial infection to increase in a population that experiences flooding. This is evidenced by a reported four deaths from leptospirosis due to flooding in Puerto Rico.

What are leptospirosis symptoms and signs?

The symptoms and signs of leptospirosis are variable and are similar to those seen in many other diseases (dengue fever, hantavirus, brucellosis, malaria, and others). Symptoms can arise about two days to four weeks after exposure to the bacteria. Although some people have no symptoms, others may exhibit

These symptoms usually occur in the first phase of the infection, and when present, they often occur abruptly. Some patients resolve their symptoms and do not progress to the second phase. Others may seem to briefly recover but relapse (about 5%-10%) with more severe symptoms and organ damage in the severe form of the disease. The second-phase symptoms may overlap with the first-phase symptoms in severe disease and include the following:

This is the second phase of leptospirosis, called Weil's disease. If it's not treated, it may not resolve for several months, and some patients may develop long-term complications such as kidney and lung problems. The death rate is about 1%-5%.

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What specialists treat leptospirosis?

Clinic doctors, primary care doctors, pediatricians, and emergency-medicine specialists often treat leptospirosis in countries where it is endemic and the patients are in the first phase of the disease. Other specialists are often consulted if the patient begins to enter the second phase of the disease. These specialists may include critical care, infectious-disease, hospitalists, internists, pulmonologists, cardiologists, and kidney specialists.

How do physicians diagnose leptospirosis?

Physicians make a presumptive diagnosis based on the patient's history and physical exam. Only specialized labs perform serological serology tests for leptospirosis serogroups (specific types of the bacteria that react with certain antibodies). Health care professionals may perform definitive tests by isolating the bacteria from the patient (blood or CSF) or by a positive microscopic agglutination test (MAT). Other tests (ELISA, PCR, urine dipsticks) may provide additional evidence of infection. Patients with severe symptoms should be treated as confirmatory tests are time consuming.

What is the treatment for leptospirosis?

Although there is controversy about using antibiotics in the first phase of leptospirosis, antibiotics (penicillin – penicillin G, ampicillin [Omnipen, Polycillin, Principen], amoxicillin [Amoxil, Trimox, Moxatag, Larotid], or erythromycin [E-Mycin, Eryc, Ery-Tab, PCE, Pediazole, Ilosone]) are recommended for treatment of patients with phase two or more severe symptoms. Some patients may require IV antibiotics and supportive hospital care such as rehydration.

For those clinicians who choose to treat phase-one patients, the choice of antibiotics includes the above, but many choose to treat with doxycycline.




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What is the prognosis of leptospirosis?

Overall, the prognosis of leptospirosis is good. Many people become infected and spontaneously recover without treatment. However, the prognosis worsens as the symptoms increase. People with Weil's disease may have a prognosis ranging from good to poor, depending on their response to treatment. Pregnant women who become infected have a high rate of fetal mortality, especially if they acquire the disease early in pregnancy.

Is a vaccine available for leptospirosis? Is it possible to prevent leptospirosis?

A leptospirosis vaccine is not currently available in the U.S.; however, high-risk workers in some European and Asian countries may have access to a vaccine. Unfortunately, the vaccines are serovar-specific (bacterial-strain specific) and thus do not offer widespread protection as there are over 200 serovars (immunologically distinct types of the bacteria). Some vaccines are available for animals but these, like the human vaccines, are only effective against a narrow range of serovars. In addition, side effects of the vaccine can cause painful swelling. Chemoprophylaxis (using drugs to prevent illness) is possible under certain circumstances. Some individuals who may have high short-time risk (for example, military personnel) may take doxycycline (200 mg/week), beginning one to two days before potential exposure to have about a 95% chance of preventing infection with chemoprophylaxis. This preventive treatment is not recommended for long terms of exposure.

Avoiding contact with animal excrement, good hygiene, and avoiding contaminated water and soil are other ways to reduce the chance of getting leptospirosis.

Dogs, and many other animals, can be infected with leptospirosis. Veterinarians have access to vaccines that can protect (or prevent) leptospirosis in dogs and other animals for at least 12 months. This vaccination may help protect the animals' owners and other local or family owned animals from the disease for approximately one year.

Typhoid Fever Vaccine, Symptoms, Causes, Diagnosis & Treatment

Typhoid fever facts

Illustration of Typhoid Fever Images for Illustration of Typhoid Fever

  • Usually, Salmonellae typhi bacteria causes typhoid fever.
  • People contract typhoid fever by ingesting contaminated food or water.
  • Diagnosis of typhoid fever is made when the Salmonella bacteria is detected with a stool culture.
  • Antibiotics treat typhoid fever.
  • Typhoid fever symptoms are
    • poor appetite,
    • headaches,
    • diarrhea,
    • generalized aches and pains,
    • fever, and
    • lethargy.
  • Approximately 3%-5% of patients become carriers of the bacteria after the acute illness.
  • For those traveling to high-risk areas, typhoid vaccines are now available
  • There are two forms of the vaccine available, an oral and an injectable form.

Typhoid Fever Prevention

Vaccine

Typhoid fever is an acute febrile illness caused by the bacterium Salmonella typhi. It is spread by contaminated food and water. Although quite common at one time in the U.S., it is very rare today. Most cases are in people who have traveled outside the U.S. Worldwide, the disease affects 13 million people. People who are traveling to areas with high rates of typhoid fever should receive the vaccine prior to leaving the U.S. Travelers should consult the CDC web site for specific recommendations depending on the countries they plan to visit (http://wwwn.cdc.gov/travel/).

Learn more about travel vaccinations »

What is typhoid fever? What is the history of typhoid fever?

Typhoid fever is an acute infectious illness associated with fever that is most often caused by the Salmonella typhi bacteria. Salmonella paratyphi, a related bacterium that usually leads to a less severe illness, can also cause typhoid fever. The feces of human carriers of the bacteria may contaminate water or food, and the illness then spreads to other people in the area. Typhoid fever is rare in industrial countries but continues to be a significant public health issue in developing countries.

The incidence of typhoid fever in the United States has decreased since the early 1900s. In 2014, medical professionals reported approximately 300 cases to the CDC, mostly in people who recently traveled to endemic areas. This is in comparison to the 1920s, when there were over 35,000 reported cases in the U.S., with a 20% fatality rate.

In the early 1900s, a healthy carrier called Typhoid Mary (her real name was Mary Mallon) caused several outbreaks in the New York City area; she was infected, worked as a cook, and consequently spread the disease to others.

A recent outbreak affected refugees in Manus Island, Papua New Guinea.

The decrease in cases in the United States is the result of improved environmental sanitation, vaccination, and treatment with antibiotics. Mexico and South America are the most common areas for U.S. citizens to contract typhoid fever. India, Pakistan, and Egypt are also known high-risk areas for developing this disease. Worldwide, typhoid fever affects more than 21 million people annually, with over 200,000 patients dying of the disease.

If traveling to endemic areas, you should consult with your health care professional and discuss if you should receive vaccination for typhoid fever.

How do patients get typhoid fever?

People contract typhoid fever when they ingestion the bacteria in contaminated food or water. Patients with acute illness can contaminate the surrounding water supply through stool, which contains a high concentration of the bacteria. Contamination of the water supply can taint the food supply. About 3%-5% of patients become carriers of the bacteria after the acute illness. Some patients suffer a very mild illness that goes unrecognized. These patients can become long-term carriers of the bacteria. The bacteria multiply in the gallbladder, bile ducts, or liver and passes into the bowel. The bacteria can survive for weeks in water or dried sewage. These chronic carriers may have no symptoms and can be the source of new outbreaks of typhoid fever for many years.

What causes typhoid fever? How do health care professionals diagnose typhoid fever?

After the ingestion of contaminated food or water, the Salmonella bacteria invade the small intestine and enter the bloodstream temporarily. White blood cells carry the bacteria to the liver, spleen, and bone marrow. The bacteria then multiply in the cells of these organs and reenter the bloodstream. Patients develop symptoms, including fever, when the organism reenters the bloodstream. Bacteria invade the gallbladder, biliary system, and the lymphatic tissue of the bowel. Here, they multiply in high numbers. The bacteria pass into the intestinal tract and can be identified for diagnosis in cultures from the stool tested in the laboratory. Stool cultures are sensitive in the early and late stages of the disease, but it may be necessary to perform blood cultures to make a definitive diagnosis.

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What are the signs and symptoms of typhoid fever?

The incubation period is usually 1-2 weeks, and the duration of the illness is about 4-6 weeks. The patient experiences

People with typhoid fever usually have a sustained fever as high as 103 F-104 F (39 C-40 C).

Chest congestion develops in many patients, and abdominal pain and discomfort are common. The fever becomes constant. Improvement occurs in the third and fourth week in those without complications. About 10% of patients have recurrent symptoms (relapse) after feeling better for 1-2 weeks. Relapses are actually more common in individuals treated with antibiotics.




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What is the treatment for typhoid fever, and what is the prognosis?

Antibiotics that kill the Salmonella bacteria treat typhoid fever. Prior to the use of antibiotics and intravenous fluids, the fatality rate was 20%. Death occurred from overwhelming infection, pneumonia, intestinal bleeding, or intestinal perforation. Antibiotics and supportive care have reduced the mortality rate to 1%-2%. With appropriate antibiotic therapy, there is usually improvement within one to two days and recovery within 7 to 10 days.

Several antibiotics are effective for the treatment of typhoid fever. Chloramphenicol was the original drug of choice for many years. Because of rare serious side effects, other effective antibiotics have replaced chloramphenicol. The choice of antibiotics needs to be guided by identifying the geographic region where the organism was acquired and the results of cultures once available. (Certain strains from South America show a significant resistance to some antibiotics.) Ciprofloxacin (Cipro) is the most frequently used drug in the U.S. for nonpregnant patients. Ceftriaxone (Rocephin), an intramuscular injection medication, is an alternative for pregnant patients. Ampicillin (Omnipen, Polycillin, Principen) and trimethoprim (Bactrim, Septra) are frequently prescribed antibiotics although resistance has been reported in recent years.

Medical professionals have reported multi-drug resistance and use cultures to guide treatment. If relapses occur, patients are retreated with antibiotics.

Prolonged antibiotics can treat the carrier state, which occurs in 3%-5% of those infected. Often, removal of the gallbladder, the site of chronic infection, will cure the carrier state.

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What specialists treats typhoid fever?

Your primary care doctor can diagnose and treat typhoid fever. Because the disease is very rare in the United States, an infectious disease specialist often assists in the care of the patient with typhoid fever, as well.

Is typhoid fever contagious?

Typhoid fever is very contagious and contracted by the ingestion of the bacteria in contaminated food or water. Patients with acute illness can contaminate the surrounding water supply through infected stool, which contains a high concentration of the bacteria. It does not spread through the air (by cough) or by touching (assuming there is no fecal exchange or first bacterial ingestion).

Is it possible to prevent typhoid fever?

For those traveling to high-risk areas, typhoid vaccines are now available. The routine administration of the vaccine is usually not recommended in the U.S. There are two forms of the vaccine available, an oral and an injectable form. People need to complete the vaccination at least 1-2 weeks (depending on the type of vaccine) prior to travel and, depending on the type of vaccine. The vaccine only protects from 2 to 5 years. The oral vaccine is contraindicated in patients with depressed immune systems. Details of the vaccination and the choice of vaccine should be discussed with a health care professional.

Travelers’ Diarrhea Treatment, Symptoms & Prevention

Travelers’ diarrhea facts

DiarrheaTravelers' diarrhea is commonly accompanied by abdominal cramps, nausea, and bloating.

  • Travelers' diarrhea is a gastrointestinal illness that occurs in travelers.
  • Travelers' diarrhea usually is caused by eating food contaminated with bacteria or, less commonly, with parasites or viruses.
  • The treatment of travelers' diarrhea is usually plenty of oral liquids as well as over-the-counter medications that control diarrhea and cramps.
  • Antibiotic prophylaxis (prevention) for travelers' diarrhea is available but is not recommended generally.
  • The prognosis of travelers' diarrhea is good. It is rarely fatal, and most cases resolve within a week.

What is travelers’ diarrhea?

Travelers' diarrhea is defined by most experts as three or more unformed stools in a 24 hour time period, passed by a person who is traveling. Travelers' diarrhea is commonly accompanied by abdominal cramps, nausea, and bloating. Travelers' diarrhea is a general term and does not specify any cause. Travelers' from temperate regions of the world frequently experience diarrhea four days to two weeks after arriving in certain other areas of the world. Other terms used to describe this illness include "Montezuma's Revenge," the "Aztec Two Step," and "Turista" in Mexico, the "Delhi Belly" in India, and the "Hong Kong Dog" in the Far East.

How common is travelers’ diarrhea?

Twenty percent to 50 percent of international travelers may develop diarrhea depending on the region of the world they visit. Diarrhea is the most common illness of travelers, affecting 10 million people each year, according to the Centers for Disease Control (CDC). In general, travelers at risk for diarrhea commonly come from industrialized nations and travel to high-risk areas that are primarily within developing or less industrialized nations of the world, including Latin America, Africa, the Middle East, and Asia. Areas of lesser risk include China and some Caribbean nations. Travel to areas of the United States, Canada, Northern Europe, and Australia pose the lowest risk to travelers.

Men and women are at equal risk for developing travelers' diarrhea. Younger individuals are more commonly afflicted, perhaps because of more adventurous eating habits. People with disorders that compromise their immune system (such as HIV, cancer, chemotherapy, steroid use), people with diabetes, and people with underlying abdominal disorders (irritable bowel syndrome, colitis) are more susceptible to travelers' diarrhea. People taking acid blockers for their stomachs (for example, famotidine [Pepcid], cimetidine [Tagamet], omeprazole [Prilosec], esomeprazole [Nexium]) also have a higher susceptibility to travelers' diarrhea because they have less stomach acid to protect them from the bacteria that cause the condition.

9 Tips to Prevent Travelers’ Diarrhea

Medical Author:

Melissa Conrad Stöppler, MD
Medical Editor:

Charles P. Davis, MD, PhD

Travelers’ diarrhea strikes up to half of all international travelers. It is
far and away the most common travel-related illness, affecting about 10 million
people per year worldwide. Infectious agents, particularly bacteria from water
contaminated with feces, cause travelers’
diarrhea. The most commonly identified bacteria associated with travelers’
diarrhea are what are called ETEC, or enterotoxigenic
Escherichia coli
.

The destination is the most important risk factor for the development of
travelers’ diarrhea. Developing countries all over the world represent the
highest risk, and the highest-risk destinations are the developing countries of
Latin America, Africa, the Middle East, and Asia. Certain groups of people are
also more likely to develop travelers’ diarrhea. At-risk groups include:

  • immunosuppressed persons,
  • those with diabetes, and
  • persons with inflammatory
    bowel diseases.

Learn the 9 tips to prevent travelers’ diarrhea »

What causes travelers’ diarrhea?

Travelers' diarrhea usually is contracted by the ingestion of contaminated food or water. Contrary to common belief, food – not water – is the primary cause. The CDC estimates up to 80% of cases of travelers' diarrhea are caused by bacteria. The most common bacterium that causes travelers' diarrhea is enterotoxigenic E. coli, one of six classes of enterovirulent E. coli.

Most E. coli are harmless. However, there are six unique classes of E. coli that can cause inflammation of the stomach and bowels (gastroenteritis) and are termed enterovirulent. They are virulent (extremely noxious) to the intestine (or, in Greek, the enteron).

Collectively, these six classes of enterovirulent E. coli are referred to as the EEC group (enterovirulent E. coli). Each class of EEC is distinct and different from the others.

  • Enteroinvasive E. coli (EIEC) invades (passes into) the intestinal wall to produce severe diarrhea.
  • Enterohemorrhagic E. coli (EHEC) is a type of EHEC, E.coli 0157:H7 that can cause bloody diarrhea and hemolytic uremic syndrome (anemia and kidney failure).
  • Enterotoxigenic E. coli (ETEC) is the one that causes most travelers' diarrhea and produces a toxin that acts on the intestinal lining.
  • Enteropathogenic E. coli (EPEC) can cause diarrhea outbreaks in newborn nurseries.
  • Enteroinvasive E. coli (EIEC) invade the epithelial cells causing diarrhea with mucus and blood.
  • Enteroaggregative E. coli (EAggEC) can cause acute and chronic (long-lasting) diarrhea in children.

Other bacterial species implicated in travelers' diarrhea include Campylobacter jejuni, Shigella, and Salmonella. Viruses (including Rotavirus, Norwalk virus and other enteric viruses) less commonly are causes of travelers' diarrhea. Parasitic infections are an uncommon cause except Giardia lamblia, which should be suspected in individuals traveling to Russia or mountainous regions of the Northern Hemisphere. Cryptosporidum, another parasite, also has been implicated as a common cause of diarrhea in visitors to St. Petersburg, Russia, and elsewhere.




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What are the symptoms of travelers’ diarrhea?

The symptoms of travelers' diarrhea vary. Generally, diarrhea occurs within the first week of travel and lasts up to three to four days.

  • Affected individuals on average pass up to five loose or watery bowel movements per day, which may be associated with cramps.
  • On occasion, individuals may experience fever or bloody stools.
  • Diarrhea may be accompanied by
    • abdominal pain and cramping,
    • bloating, or
    • an increase in stomach or
    • intestinal noises or
    • gurgling (borborygmi).

How is travelers’ diarrhea diagnosed?

The presumptive diagnosis of travelers' diarrhea is based solely on the development of diarrhea when visiting a part of the world where this condition is common among travelers. Diarrhea usually is mild, self-limited, and resolves spontaneously. Symptoms usually can be controlled with over-the-counter medications (see below.) Only when the diarrhea is severe or complicated, and possibly when antibiotics are contemplated, should attempts be made to identify the exact organism responsible for diarrhea so that the correct drug therapy can be selected. Identification may be difficult or impossible in undeveloped countries because of the lack of medical laboratories. When laboratories are available, the stool can be examined for parasites and cultured for bacteria. Identification of the pathogen results in a definitive diagnosis.

How is travelers’ diarrhea treated?

Although prophylactic antibiotics (antibiotics are taken before the person is exposed to the pathogen) are effective in preventing travelers' diarrhea, they generally are not recommended. The side effects of antibiotics, including photosensitivity (sensitivity to the sun that results in injury to the skin) and additional diarrhea, can be major problems. Antibiotic prophylaxis can be considered in individuals with underlying medical diseases in whom diarrhea is more likely to occur or who may be profoundly affected by diarrhea. This group includes people with previous stomach surgery, active inflammatory bowel disease, underlying immunodeficiency conditions, and other serious medical disorders. In these situations, drugs of the quinolone class (ciprofloxacin [Cipro, Cipro XR, Proquin XR], levofloxacin [Levaquin]) have been shown to be effective.

Bismuth subsalicylate (Pepto-Bismol) in liquid or pill form also has been shown to be effective in preventing diarrhea in up to 65% of travelers although Pepto-Bismol may cause black stools and, rarely, ringing in the ears. People allergic to aspirin should avoid Pepto-Bismol.

When treating afflicted individuals, drugs that alleviate symptoms, as well as antibiotics, play a role. With moderate symptoms, the addition of Pepto-Bismol alone may suffice. Alternatively, anti-diarrheal agents such as diphenoxylate and atropine (Lomotil) or loperamide (Imodium) can be given. With severe disease, characterized by frequent diarrhea or dehydration, or complicated by the passage of bloody stools, Lomotil or Imodium should not be used and you should consult your doctor.

Oral fluids are a mainstay of therapy since they are important to prevent dehydration. Tips for staying hydrated are:

  • Small, frequent sips of clear liquids (those you can see through) are the best way to stay hydrated.
  • Avoid alcoholic, caffeinated, or sugary drinks, if possible. Over-the-counter rehydration products made for children such as Pedialyte and Rehydralyte are expensive but good to use if available.
  • Sports drinks such as Gatorade and PowerAde are fine for adults if they are diluted with water because at full strength they contain too much sugar, which can worsen diarrhea.
  • Try to drink at least as much or more fluid than you think is coming out or lost with watery diarrhea.
  • For mild to moderate dehydration, oral rehydration salts (ORS) may be recommended. These are available in pharmacies in most developing countries. Severe hydration usually requires emergent intravenous rehydration (IV).
  • If the affected individual cannot hold down fluids or is losing fluids faster than they can take them in, seek medical care immediately because some patients will require IV hydration.

Children and the elderly are more susceptible to dehydration. If a person feels light-headed or woozy, feels a rapid pulse or their mouth and lips are dry, they should consult a physician. If a child is listless, not eating or drinking, and does not make wet diapers or urinate within a few hours, they also should be seen quickly by a doctor.

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What is the prognosis for travelers’ diarrhea?

The prognosis for travelers' diarrhea is usually good.

  • Most cases resolve within 2 days without treatment.
  • The CDC estimates 90% of cases resolve within one week, and 98% resolve within one month.
  • Travelers' diarrhea is rarely fatal.

How can travelers’ diarrhea be prevented?

Since food is the major source of infection, close attention to diet is of foremost importance in the prevention of travelers' diarrhea.

  • Foods should be well-cooked and served warm.
  • Raw vegetables, uncooked meat or seafood, and other foods maintained at room temperature should be avoided.
  • Dairy products, tap water, and ice (including frozen drinks not made from filtered water) are also high-risk foods.
  • Carbonated beverages, beer and wine, hot coffee and tea, fruits that can be peeled, and canned products generally are safe.
  • The risk for developing diarrhea increases when eating at restaurants and when purchasing food from street vendors.
  • Also, frequent hand washing with soap and clean water will decrease the likelihood of the bacteria's spread, especially to other people that the person may be traveling with.

Antibiotics can be effective in preventing travelers' diarrhea but are not recommended for most people due to possible side effects (see "How is Travelers' Diarrhea Treated?").

Bismuth subsalicylate (Pepto-Bismol) also can be effective in preventing diarrhea in travelers although Pepto-Bismol may cause black stools and, rarely, ringing in the ears. People allergic to aspirin should avoid Pepto-Bismol. Studies have not shown bismuth subsalicylate to be safe for use longer than three weeks.

Probiotics such as Lactobacillus have shown inconclusive results in the prevention of travelers' diarrhea.

What Causes Typhoid Fever?

What is typhoid fever?

Typhoid fever is typically caused by a bacteria called Salmonella typhi, which only infects and sickens humans. Typhoid fever is typically caused by a bacteria called Salmonella typhi, which only infects and sickens humans.

Typhoid fever, or paratyphoid fever, is a bacterial illness that causes a prolonged high fever, diarrhea, and body rash. It's typically caused by a bacteria called Salmonella typhi, which only infects and sickens humans. A related strain, Salmonella paratyphi, can infect domestic animals and humans, causing a similar disease known as paratyphoid fever. 

You catch typhoid fever when you consume food or water that's been contaminated with Salmonella. The disease is rare in developed countries but is a significant public health issue in developing countries. Communities with poor water and sanitation regulation are most at risk for outbreaks of typhoid fever. 

Symptoms of typhoid fever

Typhoid fever causes a sustained fever, or a temperature that doesn't come and go. Once infected, your fever could climb as high as 104 degrees Fahrenheit.

Early symptoms often include fever, stomach pain, and fatigue

You may also experience:

Causes of typhoid fever

Salmonella typhi bacteria are spread by eating food and drinking water that's been contaminated. The bacteria are found in the stool of an infected person or by someone who is a carrier. Carriers have recovered from typhoid fever, but still carry the bacteria and can infect others.

Typhoid fever is often a result of poor hygiene practices. The bacteria may end up in someone's hands or another part of the body. It's also possible to contract typhoid if the water used to wash food or prepare drinks is contaminated with Salmonella-laced sewage. 




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When to see a doctor for typhoid fever

Typhoid fever can be dangerous and life-threatening. Untreated typhoid fever can cause complications like bradycardia, hepatosplenomegaly, or pneumonia. It is important to call your doctor as soon as you notice symptoms, especially if you know you have been exposed. If you are still traveling when you begin to notice symptoms, call the U.S. consulate for help.

Beyond the threat to your health, it is important to diagnose and treat your typhoid fever so you don’t spread the disease. Even after your symptoms subside, you may still be a carrier for Salmonella typhi. Get a series of stool cultures until you know you are no longer carrying the bacteria.

Diagnosing typhoid fever

Physical tests for typhoid fever can be unreliable. Your doctor will often use your symptoms, a physical examination, and your travel history to make a diagnosis. 

They may still run a stool sample to look for the presence of Salmonella typhi bacteria. Or a blood test can indicate tpyhoid fever with elevated white blood cell counts.

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Preventing typhoid fever

There's a vaccine that can help prevent typhoid fever. It's recommended if you're traveling outside the U.S. to a country where typhoid fever is common. When traveling practice these safety precautions: 

  • Drink bottled or boiled water. 
  • Eat food that's fully cooked. 
  • Wash your hands before eating and drinking. 
  • Don't eat raw vegetables or fruits that can’t be peeled. 

Some travelers carry electrolyte packets to prevent dehydration from foodborne illnesses like typhoid. 

Treatments for typhoid fever

If there's a chance you've been exposed to typhoid fever, see a healthcare provider immediately. Sometimes, the disease will go away on its own, but it can last for weeks or months without treatment: 

Your treatment plan will involve a course of antibiotics. The medication and length of time you take them depend on your age, symptoms, and general health. 

Once you start taking the medication, it's important to: 

  • Finish the full course of treatment.
  • Wash your hands after using the bathroom.
  • Avoid preparing food for other people.
  • Have a series of stool cultures to ensure the bacteria is no longer in your body. 

Symptoms of typhoid fever usually subside after treatment. Follow up with your doctor to check if you are still a carrier. Also contact your doctor if you struggle with persistent fever and weakness, as you could have complications from typhoid fever.

What Is the Best Treatment for Typhoid Fever?

What is typhoid fever?

The best treatment for typhoid fever is antibiotics. However, some strains of typhoid fever have become resistant to antibiotics.The best treatment for typhoid fever is antibiotics. However, some strains of typhoid fever have become resistant to antibiotics.

Typhoid fever is a serious bacterial infection caused by the Salmonella typhi bacterium. A similar infection called paratyphoid fever is caused by the Salmonella paratyphi bacterium.

Symptoms of typhoid fever

The most common symptoms of typhoid fever are diarrhea and a high fever that doesn't go away. Your fever may be as high as 104 degrees Fahrenheit or 40 degrees Celsius.

Other symptoms include:

Causes of typhoid fever

Typhoid fever is only caused by the bacterium Salmonella typhi. The typhoid bacteria multiply and spread through contaminated food and water. After you are infected, it can take one to three weeks for symptoms to start.

Some people become carriers of typhoid and shed the bacteria in their feces for years after they were first infected.

In fact, people who work in certain professions must have negative stool tests following their typhoid infection before they can legally return to work. This includes:

  • Childcare workers
  • Anyone who handles food
  • Healthcare workers

Those who have had typhoid fever can get it again if they are re-exposed to the bacteria.

When travelling abroad in areas where typhoid fever is common, be sure to get vaccinated. To further lower the risk of contracting the disease:

  • Drink only sealed, bottled, or treated water
  • Don't eat raw fruits and vegetables
  • Don't eat foods from street vendors

Who can get typhoid fever?

Anyone can get typhoid fever. However, this bacterium is not common in industrialized countries. It is more common in developing countries. Many cases in industrialized nations are brought back from travelers to other areas.

Vaccines are available for people traveling abroad to areas with a higher risk of contracting typhoid fever.

Diagnosis for typhoid fever

Only a licensed healthcare professional can diagnose typhoid fever. The only way for your doctor to diagnose typhoid fever is through a blood or stool test to verify the presence of the bacteria.

Your doctor will give you this test if you have symptoms of typhoid fever or were exposed to someone who recently had the infection.




QUESTION

Bowel regularity means a bowel movement every day.
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Treatments for typhoid fever

Medications

Doctors treat typhoid fever with antibiotics. However, in some parts of the world strains of typhoid fever have become resistant to most antibiotics. Doctors and researchers must continually track which antibiotics continue to offer effective treatment.

Home care

Dehydration from diarrhea is common with typhoid fever. So, you need to drink plenty of water and beverages with electrolytes. Your doctor may give you electrolyte packets to help with this.

If your condition worsens and you have to go to the hospital, doctors may give you intravenous (IV) hydration.

Complications and side effects of typhoid fever

Some people have allergic reactions to certain antibiotics. With antibiotic resistant strains, there may only be a few options for treatment.

If you are allergic to these antibiotics, it may be rather difficult to find effective medicine that you can take safely.

However, the main risk with typhoid fever is not receiving any medical treatment. One out of five people who don’t get treatment for typhoid fever die.

The risk of complications also grows if the treatment is delayed. Complications that can develop in untreated cases of typhoid fever include:

For this reason, if you have symptoms of typhoid fever, you should seek immediate medical attention. This is especially true if you have recently traveled to an area where there is a higher risk of contracting the disease.